Comparison of dexmedetomidine–propofol vs. fentanyl–propofol for laryngeal mask insertion

Üzümcügil, Filiz; Canbay, Özgür; Çelebi, Nalan; Karagöz, Ayşe Heves; Ozgen, S.

doi:10.1017/s0265021508004213

Cited by 33 publications

(58 citation statements)

References 24 publications

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“…However, in this study 26 dexmedetomidine was also continued intra-operatively. In our study, we studied patients undergoing not only lower abdominal procedures but also other surgical procedures.…”

Section: Discussionmentioning

confidence: 92%

“…To the best of our knowledge, only one earlier study 26 had evaluated dexmedetomidine with propofol to study the conditions of insertion of LMA for minor urological procedures in unpremedicated patients. However, in this study 26 dexmedetomidine was also continued intra-operatively.…”

Section: Discussionmentioning

confidence: 99%

“…In ano ther study 26 t he authors had used dexmedetomidine infusion. We have not used dexmedetomidine intraoperatively but used fentanyl in all these patients for intra-operative analgesia as our patients required different levels of analgesia according to the procedure done.…”

Section: Discussionmentioning

confidence: 99%

“…Ninety seconds after propofol injection, jaw relaxation was assessed by a 4-point score 26 and LMA of appropriate size was inserted and cuff inflated with required amount of air. Proper placement was confirmed by capnography.…”

Section: Methodsmentioning

confidence: 99%

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Comparison of dexmedetomidine combined with propofol Vs fentanyl combined with propofol for laryngeal mask insertion

Jayaram¹,

Subhadra²,

Rao³

2014

J Clin Sci Res

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Background: Few studies have assessed adequacy of anaesthesia provided by propofol in combination with dexmedetomidine and propofol in combination with fentanyl for laryngeal mask airway (LMA) insertion for minor to moderate elective surgical procedures. Methods:Sixty patients admitted for lower abdominal and lower limb surgery were randomized into Group F (n=30) and Group D (n=30). Thirty seconds after the study drug (fentanyl 1 µg/kg in Group F and dexmedetomidine 1 µg/kg in Group D diluted in 10 mL normal saline over 2 min) was administered, induction was done with i.v. propofol 2 mg/ kg in both groups. Ninety seconds after propofol injection, jaw relaxation was assessed and LMA of appropriate size was inserted. If the first attempt failed, another attempt was tried after an additional dose of i.v. propofol (0.5 mg/kg). Haemodynamic parameters, namely, heart rate, systolic blood pressure (SBP), mean blood pressure (MBP), diastolic blood pressure (DBP), arterial oxygen saturation measured with pulse oximeter and respiratory rate were recorded before and at the end of 1 st , 2 nd , 3 rd , 5 th and 10 th minutes after insertion of LMA.Results: Both the groups were comparable in age weight, sex, age wise distribution and insertion conditions. The reductions in SBP, DBP, MAP were greater in Group F (p < 0.001). More patients developed apnoea in Group F than in Group D (p < 0.05). Conclusions:Dexmedetomidine combined with propofol provides the same conditions for LMA insertion as fentanylpropofol combinations with advantage of better maintainance of haemodynamic parameters.

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Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Comparison of dexmedetomidine combined with propofol Vs fentanyl combined with propofol for laryngeal mask insertion

Jayaram¹,

Subhadra²,

Rao³

2014

J Clin Sci Res

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“…In study by Gandhi et al Dexmeditomidine (0.6 mcg/kg diluted in 5ml saline IV over 1 min) and Fentanyl (2 mcg/kg diluted in 5ml saline IV over 1 minute were used. 34 While as per Aksu et al suggest that Dexmedetomidine (0.5mcg/kg) was more effective than Fentanyl (1mcg/kg) in attenuating airway reflex responses to tracheal extubation and maintaining hemodynamic stability without prolonging recovery. 30 Till recently many studies like study by Shehabi et al and Feng et al claimed that Dexmedetomidine produced predictable falls in BP and cardiac rate in patients given Dexmedetomidine sedation in the ICU.…”

Section: Discussionmentioning

confidence: 94%

A Prospective Randomized Study of Comparison of Intravenous Fentanyl Vs Intravenous Dexmedetomidine for Attenuation of Cardiovascular Response during Laryngos copy and Tracheal Intubation in Adult Cardiac Surgery.

Umbarkar¹,

Pandhare²

2016

IOSR

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The effect of dexmedetomidine pretreatment on the median effective bolus dose of propofol for facilitating laryngeal mask airway insertion

et al. 2016

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Comparison of dexmedetomidine–propofol vs. fentanyl–propofol for laryngeal mask insertion

Abstract: BACKGROUND In search of an optimal drug for I-gel insertion, in our study, we have compared two group of drugs dexmedetomidine with propofol and fentanyl with propofol.

Cited by 33 publications

References 24 publications

Comparison of dexmedetomidine combined with propofol Vs fentanyl combined with propofol for laryngeal mask insertion

Comparison of dexmedetomidine combined with propofol Vs fentanyl combined with propofol for laryngeal mask insertion

A Prospective Randomized Study of Comparison of Intravenous Fentanyl Vs Intravenous Dexmedetomidine for Attenuation of Cardiovascular Response during Laryngos copy and Tracheal Intubation in Adult Cardiac Surgery.

The effect of dexmedetomidine pretreatment on the median effective bolus dose of propofol for facilitating laryngeal mask airway insertion

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