2017
DOI: 10.4103/0259-1162.200237
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Comparison of dexmedetomidine and magnesium sulfate as adjuvants with ropivacaine for spinal anesthesia in infraumbilical surgeries and postoperative analgesia

Abstract: Introduction:Postoperative pain is a major cause of fear and anxiety in hospitalized patients and so if patients remain pain-free during this period, they can cooperate with the circumstances well, leading to early recovery. Over the last two decades, there has been considerable revival of interest in the use of regional anesthesia techniques for surgery and pain management. As very few studies have been conducted using ropivacaine with dexmedetomidine and magnesium sulfate (MgSO4) as adjuvants, the present st… Show more

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Cited by 11 publications
(10 citation statements)
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“…[ 13 ] Makhni et al reported that DEX as an intrathecal adjuvant with ropivacaine for spinal anesthesia was better than MgSO 4 in providing early onset of sensory and motor block as well as in providing postoperative analgesia. [ 14 ] Park et al reported that DEX as an epidural adjuvant had a greater analgesic and local anesthetic-sparing effect, compared to fentanyl, in the early postoperative period in children undergoing major orthopedic lower extremity surgery. [ 12 ] In addition, it has been reported that addition of DEX to local anesthetics for brachial plexus block shortens sensory and motor block onset time and extends sensory block, motor block, and analgesia duration.…”
Section: Discussionmentioning
confidence: 99%
“…[ 13 ] Makhni et al reported that DEX as an intrathecal adjuvant with ropivacaine for spinal anesthesia was better than MgSO 4 in providing early onset of sensory and motor block as well as in providing postoperative analgesia. [ 14 ] Park et al reported that DEX as an epidural adjuvant had a greater analgesic and local anesthetic-sparing effect, compared to fentanyl, in the early postoperative period in children undergoing major orthopedic lower extremity surgery. [ 12 ] In addition, it has been reported that addition of DEX to local anesthetics for brachial plexus block shortens sensory and motor block onset time and extends sensory block, motor block, and analgesia duration.…”
Section: Discussionmentioning
confidence: 99%
“… 71 DEX as an intrathecal adjuvant with ropivacaine for spinal anesthesia provided better postoperative analgesia after infraumbilical surgeries as compared with MgSO 4 . 72 DEX as an epidural adjuvant had a greater analgesic and local anesthetic-sparing effect, compared with fentanyl, in the early postoperative period in children undergoing major orthopedic lower extremity surgery. 73 The use of DEX as an adjunct to an ilioinguinal/iliohypogastric nerve block resulted in reduced pain following pediatric inguinal hernia repair in the PACU and a prolongation of the period to first supplemental analgesia demand.…”
Section: Pharmacological Managementmentioning
confidence: 94%
“…Overall, six RCTs involving a total of 360 patients were identified for the final analysis. 9 11 , 15 – 17 Five studies included three study groups featuring comparisons among dexmedetomidine, magnesium, and saline. 9 , 10 , 15 – 17 The last study only compared dexmedetomidine and magnesium.…”
Section: Resultsmentioning
confidence: 99%
“… 9 , 10 , 15 – 17 The last study only compared dexmedetomidine and magnesium. 11 The characteristics of the eligible RCTs are displayed in Table 1 . All six articles had intermediate to high Jadad scores ( Table 1 ).…”
Section: Resultsmentioning
confidence: 99%
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