Comparison of developmental toxicity of different surface modified CdSe/ZnS QDs in zebrafish embryos

Assaying of Cu2+ with near‐infrared l‐cysteine‐capped CdSeTe/CdS quantum dots and its effect on cell imaging

“…Quantum dots (QDs) are finely dispersed semiconductor nanocrystals composed of II–IV and III–V elements with unique chemical and physical properties, [ 15,16 ] and so have attracted increasing attention and have been used widely in various fields such as optical sensors, [ 17,18 ] optoelectronics and biological imaging. [ 19,20 ] So far, many QDs‐based sensors for Cu 2+ detection have been developed such as water‐soluble glutathione capped ZnSe QDs, [ 21 ] MOF/CdTe QDs, [ 22 ] silica‐coated CdSe/ZnS QDs, [ 23 ] cysteamine‐capped CdS QDs, [ 24 ] and CdTe/CdSe QDs.…”

New insights into the safety assessment of quantum dots: potential release pathways, environmental transformations, and health risks

“…in fish. [245][246][247] The reduced motility may be due to the Ca 2+ -ATPase and Na + /K + -enzymes, which are closely linked to energy supply and motility, 245,248 or related to the change of oxidative stress state of embryos. [249][250][251][252][253][254][255] The magnitude of QDs toxicity correlates with surface functionalization and can greatly affect embryos and larvae.…”

“…256 COOH-CdSe/ZnS QDs have a higher effect on cardiac development than aminated and PEG-QDs but QDs are less toxic to multiple organ development, possibly due to Environmental Science: Nano Critical review the positively charged amino group protonation resulting in reduced uptake and toxicity. 245,247,257 The consensus view on the bioaccumulation of QDs demonstrates that QDs in fish embryos mainly gather on the surface of the chorion, and the integrity of the chorion is damaged, which has an adverse impact on embryonic development. 252,[258][259][260] When QDs spread through the chorionic pore channels of the embryo, they are deposited in the retina, brain, heart, gills, and behind the tail, causing malformations of the heart, respiratory system, and head.…”

“…in fish. 245–247 The reduced motility may be due to the Ca 2+ -ATPase and Na + /K + -enzymes, which are closely linked to energy supply and motility, 245,248 or related to the change of oxidative stress state of embryos. 249–255…”

RNA m6A Modification Alteration by Black Phosphorus Quantum Dots Regulates Cell Ferroptosis: Implications for Nanotoxicological Assessment

“…However, the safety of engineered nanomaterials (ENMs) in regards to human health and ecoenvironmental sustainability has been questioned by researchers and the public. [ 1,2 ] There are many studies show that ENMs might cause adverse effects to human or animals, such as developmental defect, [ 3 ] reproductive abnormality, [ 4 ] organ dysfunction, [ 5,6 ] and even promoting tumorigenesis. [ 7 ] Although numerous studies have been conducted for nanosafety evaluation using in silico, in vitro, and in vivo methods, a widely accepted assessment framework for ENMs remains to be built.…”