Comparison of cure rates and durations of treatment with diphenylcyclopropenone immunotherapy for warts in children/adolescents and adults

Abstract

Diphenylcyclopropenone immunotherapy can be used effectively for both children/adolescents and adults. The time required for complete cure is shorter in children/adolescents than in adults.

Factors contributing to the treatment duration of diphenylcyclopropenone immunotherapy for periungual warts

“…In our study, age, sex, disease duration, location, number of warts, and diameter of the largest wart did not show significant correlation with duration of treatment ( p > 0.05, respectively). This finding differs from our previous study, which suggested that duration of treatment was shorter in children/adolescents than in adults . It appears that the difference in study findings resulted from the small sample size in this study.…”

“…We adopted a weekly treatment schedule, unlike our previous study that used a biweekly schedule . The purpose of this change was to provide more active treatments for patients who received only DPCP immunotherapy for recalcitrant warts, and weekly treatments of DPCP have been effectively conducted in many studies .…”

“…Recent studies have shown that topical immunotherapy with DPCP is a safe and effective treatment for recalcitrant warts, including periungual types. This method is not painful and is less destructive than most other wart treatments, and it appears to be an excellent modality to treat periungual warts .…”

Clinical Efficacy of Diphenylcyclopropenone Immunotherapy as Monotherapy for Multiple Viral Warts

“…Most studies of DPCP monotherapy only included patients who had immunotherapy after the failure of conventional treatment. [11][12][13][14] This study, for the first time, only included patients who had not had any previous treatment to eliminate any cumulative effects from other treatments.…”

What factors affect the duration of treatment with diphenylcyclopropenone immunotherapy for common warts?

“…Treatment details have been described elsewhere (Park & Kim, 2016). The responses to DPCP were evaluated using the EBI and the pruritus index (PI) (Kang, Lee, Paek, Yu, & Kim, 2014). We used chi-square and multiple linear regression analyses to examine the association between treatment duration and clinical characteristics.…”