Comparison of cultured cell attachment on a temperature-responsive polymer, poly-l-lysine, and collagen using modeling curves and a thermal-controlled quartz crystal microbalance

Analysis of HepG2 cell response to a wide concentration range of mitomycin C using a multichannel quartz crystal microbalance system with a microscope

“…Therefore, QCM has been used for monitoring a chemical or biological phenomenon based on the resonant frequency change and resonant resistance or dumping factor [ [3] , [4] , [5] , [6] , [7] , [8] ]. QCM has also been used to examine the cell attachment process, focusing on the interaction between cultured cells and the surface of attached cells [ [9] , [10] , [11] , [12] , [13] , [14] , [15] , [16] , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] ]. The effects of cell density [ [9] , [10] , [11] , [12] , [13] ] and species [ [14] , [15] , [16] ] on the change in the resonant frequency of a quartz crystal have been studied.…”

“…The effects of cell density [ [9] , [10] , [11] , [12] , [13] ] and species [ [14] , [15] , [16] ] on the change in the resonant frequency of a quartz crystal have been studied. Polystyrene (hydrophobic surface), metals (hydrophilic surface), and polypeptides have been used to examine the interaction between the cell surface and cultured cells [ [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] ]. The effects of cell growth factors, inhibitors, and toxins on cell attachment and growth processes have been investigated [ [28] , [29] , [30] , [31] ].…”

“…The effects of cell growth factors, inhibitors, and toxins on cell attachment and growth processes have been investigated [ [28] , [29] , [30] , [31] ]. In these studies, the resonant resistance or dumping factor has been used to analyze the changes in cell characteristics [ [12] , [13] , [14] , [15] , [16] , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] ].…”

“…Some studies have shown that the change in the resonant frequency of quartz crystals fits with the cell attachment model curves [ 9 , 13 , 15 , 27 ]. In these studies, the cell attachment curves fitted well with the first-order lag response curves [ 13 , 27 ].…”

“…Some studies have shown that the change in the resonant frequency of quartz crystals fits with the cell attachment model curves [ 9 , 13 , 15 , 27 ]. In these studies, the cell attachment curves fitted well with the first-order lag response curves [ 13 , 27 ]. In this study, transparent indium-doped tin oxide (ITO) electrodes served as the electrodes of the quartz crystal, enabling the simultaneous acquisition of transparent cell images and resonant frequency measurements.…”