Comparison of Corneal Thickness Measurements Using Galilei, HR Pentacam, and Ultrasound

Hosseini, Hamid; Katbab, A; Khalili, Mohammad Reza; Abtahi, Mohammad Bagher

doi:10.1097/ico.0b013e3181cf98e5

Cited by 47 publications

(19 citation statements)

References 31 publications

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“…In accordance with our data, previous studies also found that the Pentacam system underestimated the CCT value as compared to the Galilei system [14], and the Sirius system provided slightly higher TCT measurements compared to that obtained from the Pentacam system [18]. Different results, however, have been reported by other studies.…”

Section: Discussionsupporting

confidence: 91%

“…Previous studies have compared CCT and/or thinnest corneal thickness (TCT) measurements obtained by some of these instruments, such as between a single rotating Scheimpflug camera, the Pentacam (Oculus, Wetzlar, Germany) and a single rotating Scheimpflug camera combined with a Placido disc corneal topographer, the Sirius (Costruzione Strumenti Oftalmici, Florence, Italy) [18], [19]; between the Pentacam and a dual Scheimpflug camera combined with a Placido disc corneal topographer, the Galilei (Ziemer, Port, Switzerland) [14]; and between the Pentacam and the RTVue-100 FD-OCT (Optovue Inc., Freemont, CA, USA) [13], [20]–[22]. Other studies have assessed the agreement between MPCT measurements [9], [22].…”

Section: Introductionmentioning

confidence: 99%

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Central and Midperipheral Corneal Thickness Measured with Scheimpflug Imaging and Optical Coherence Tomography

et al. 2014

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PurposeTo compare corneal thickness measurements using Pentacam (Oculus, Germany), Sirius (CSO, Italy), Galilei (Ziemer, Switzerland), and RTVue-100 OCT (Optovue Inc., USA).MethodsSixty-six eyes of 66 healthy volunteers were enrolled. Three consecutive measurements were performed with each device. The mean value of the three measurements was used for subsequent analysis. Central corneal thickness (CCT), thinnest corneal thickness (TCT), and midperipheral corneal thickness (MPCT; measured at superior, inferior, nasal, and temporal locations with a distance of 1 mm (CT2mm) or 2.5 mm (CT5mm) from the corneal apex) were analyzed. Differences and agreement between measurements were assessed using the repeated-measures analysis of variance (ANOVA) and Bland-Altman analyses, respectively.ResultsStatistically significant differences (p<0.001) among the four devices were revealed in CCT, TCT and CT2mmmeasurements. The CCT, TCT, and CT2mm values were ranked from the thickest to the thinnest as follows: Galilei>Sirius>Pentacam>RTVue OCT. For these measurements, agreement between measurements by Sirius and Pentacam was good, whereas Galilei overestimated and RTVue underestimated corneal thickness compared to Sirius and Pentacam. As regards CT5mm measurements, Pentacam provided the largest values, whereas RTVue OCT yielded the smallest values. Agreement of the CT5mm measurements was good between the Pentacam, Sirius, moderate between Galilei and the other two Scheimpflug systems, and poor between the RTVue OCT and the remaining devices.ConclusionsThe Pentacam and Sirius can be used interchangeably for CCT measurements, while the Galilei and RTVue systematically over- and underestimate CCT, respectively. The three Scheimpflug cameras, but not the RTVue, may be used interchangeably for MPCT measurements.

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Central and Midperipheral Corneal Thickness Measured with Scheimpflug Imaging and Optical Coherence Tomography

et al. 2014

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“…Compared to recent GSA studies in normal subjects, CCT values in this study were similar. A mean value of 549.2±30.5 µm for 77 normal eyes was reported by Zaina, which is thicker than the 541.27±30.07 µm for 92 eyes in a study by Ladi et al, but thinner than the 560.57±29.10 µm reported for 47 eyes by Hosseini et al [18]–[20] A number of factors may affect CCT, such as age, race, gender, refractive error, and corneal curvature. [8]–[10] In our study, we found that CCT decreased approximately 3.2 µm for each decade of increase in age.…”

Section: Discussionmentioning

confidence: 76%

Evaluation of Anterior Segment Parameters and Possible Influencing Factors in Normal Subjects Using a Dual Scheimpflug Analyzer

Wang

Dong

2014

PLoS ONE

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PurposeTo investigate normal anterior segment parameters and analyze the possible influencing factors using a dual Scheimpflug system.SettingDepartment of Ophthalmology, Affiliated Sixth People's Hospital Shanghai Jiao Tong University, Shanghai, China.DesignA prospective observational case series.MethodsA total of 153 normal subjects (153 eyes) were studied. The anterior segment parameters, including the central corneal thickness (CCT), anterior chamber depth (ACD), pupil diameter (PD), keratoconus prediction index (KPI), simulated keratometry (SimK) values, anterior instantaneous curvature (AIC), posterior axial curvature (PAC), corneal eccentricity, total corneal power (TCP), axial curvature (AC), total corneal wavefront (TCW), high order aberration (HOA), and spherical aberration (SA), were determined using a dual Scheimpflug analyzer.ResultsThe CCT and ACD were both negatively correlated with age (r = −0.203, p = 0.012; r = −0.589, p<0.001). There was no significant difference in the refractive indices of AIC and SimK. Compared with the negative correlation of HOA and SA (r = −0.358, p<0.001), a positive correlation was found between TCW and HOA (r = 0.561, p<0.001). Unlike the decreased tendency of AC, the TCP increased gradually from the center to the periphery in the central 8 mm diameter. TCP showed a significant correlation with AC in the analyzed area.ConclusionsAIC and SimK provide different information in clinic, but the refractive indices of them showed no difference in this healthy study population, and age should be considered when using CCT and ACD values.

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“…Corneal thickness is considered an important indicator of corneal health, and it can be evaluated through the use of several methods, including ultrasonic pachymetry, optical slit-lamp pachymetry, confocal microscopy, specular microscopy, and partial coherence interferometry. Several reports have found corneal thickness measurements performed by the Pentacam and its pachymetric map to be reliable and reproducible [5,[23][24][25][26].…”

Section: Discussionmentioning

confidence: 99%

Corneal Evaluation in Healthy Brazilian Children Using a Scheimpflug Topography System

Is¹,

Mf²,

Camila³

et al. 2017

J Clin Exp Ophthalmol

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Purpose: To identify the distribution and variation in corneal topography, thickness, and elevation in healthy Brazilian children as measured by the Pentacam Scheimpflug system (Oculus Optikgeräte GmbH, Wetzlar, Germany). Methods:Healthy children between 7 and 11 years of age were scanned using the Pentacam Scheimpflug corneal topography system (Oculus Optikgeräte GmbH, Wetzlar, Germany). The exclusion criteria were inability to undergo the ocular exam, history of any ocular diseases (including strabismus, amblyopia, cataracts, retinal disorders, and allergic conjunctivitis), and topographic diagnosis of corneal ectasia based on the modified Rabinowitz/McDonnell criteria for keratoconus. The right eye of each subject was selected for analysis. The parameters evaluated were central corneal thickness (CCT), thinnest pachymetry (TP), average pachymetric progression index (PPIave), anterior and posterior elevation (AE and PE), anterior and posterior best fit sphere (ABFS and PBFS), pachymetric difference between the apex and the thinnest point (PDAT), Ambrosio's relational thickness (ARTMax), overall Belin/Ambrósio Enhanced Ectasia display score (BAD-D), simulated keratometry (SimK), astigmatism in SimK (SimK astig), maximum keratometry (K max), asphericity (Q value), and anterior chamber depth (ACD).Results: A total of 160 children (69 male, 91 female) were included in this study. The mean age of the children was 8.82 ± 1.23 years (ranging from 7 to 11 years). The mean CCT was 553.81 ± 32 µm, and mean TP was 547.95 ± 32.06 µm. The TP was most commonly located in the inferotemporal quadrant in 93.125% (149) eyes. The mean PPIave was 1.00 ± 0.14, similar to that of normal adults. The mean ABFS and PBFS values were 7.49 ± 3.26 and 10.54 ± 6.25, respectively. ART Max and D averaged 446.57 ± 81.20 and 0.78 ± 0.65, respectively. Mean ± SD values for SimK, SimK astig, and K max were 43.35 ± 1.31 D, 0.92 ± 0.66 D, and 44.40 ± 1.45 D respectively. The K max and SimK astig values were close to those reported by other topographic systems for children. Q value and ACD averaged -0.39 ± 0.12 and 3.065 ± 0.2745 mm. Conclusion:This study provides normative values for corneal topography, thickness, and elevation in healthy Brazilian children. These results may provide helpful information for diagnosis of corneal diseases in children. Further studies are needed to evaluate the role of tomography in identifying early forms of ectasia in this age group.

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Comparison of Corneal Thickness Measurements Using Galilei, HR Pentacam, and Ultrasound

Cited by 47 publications

References 31 publications

Central and Midperipheral Corneal Thickness Measured with Scheimpflug Imaging and Optical Coherence Tomography

Central and Midperipheral Corneal Thickness Measured with Scheimpflug Imaging and Optical Coherence Tomography

Evaluation of Anterior Segment Parameters and Possible Influencing Factors in Normal Subjects Using a Dual Scheimpflug Analyzer

Corneal Evaluation in Healthy Brazilian Children Using a Scheimpflug Topography System

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