Comparison of cord blood pro‐BNP levels in newborns of SARS‐COV‐2‐positive and ‐negative women, and its association with adverse perinatal outcomes

Abstract

Objective: To compare umbilical cord blood pro-B-type natriuretic peptide (BNP) levels in newborns of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) positive pregnancies to those of SARS-COV-2 negative pregnancies. Methods:Prospectively cord blood samples from newborns of 42 SARS-COV-2 positive women, and 42 negative pregnant were collected at birth and analyzed for pro-BNP levels. Results:The mean cord blood pro-BNP level was significantly higher in newborns of SARS-COV-2 positive women than in controls. Furthermore, the pro-BNP level was an independent predictor of NİCU admission in both SARS-COV-2 positive and control patients. Conclusion:Cord blood pro-BNP level may be a parameter that can predict the understress fetus and adverse perinatal outcomes especially, in cases where placental involvement is present as in SARS-COV-2 infection.