Comparison of conventional reconstruction plate versus direct metal laser sintering plate: an in vitro mechanical characteristics study

Xie, Pusheng; Ouyang, Hui; Deng, Yong; Yang, Yang; Xu, Jing; Huang, Wenhua

doi:10.1186/s13018-017-0628-6

Cited by 10 publications

(11 citation statements)

References 25 publications

(29 reference statements)

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“…They may be an alternative choice for fixation treatments of humerus fractures in clinical applications. [14]. Ayrıca aynı çalışmada eklemeli imalat yöntemi ile üretilen numunelerin, talaşlı imalat yöntemi ile üretilenlere kıyasla daha yüksek dayanım değerlerine sahip oldukları ortaya konulmuştur.…”

Section: Investigation On Manufacturability Of Bone Plates Used In Huunclassified

“…Kemik doku ortalama yaklaşık olarak 3 ila 4 ay arasında tam olarak iyileşme göstermektedir. Kemik dokunun günlük ortalama 5000 ila 14000 çevrime maruz kaldığı dikkate alınırsa, iyileşme süreci içerisinde 0,5 ila 1,6 milyon çevrime maruz kalacağı öngörülmektedir [14,15]. Yorulma deneyleri sonunda kemik plakaların 4,5 Nm yükleme değerinin altındaki koşullarda herhangi bir kırılma durumu ile karşılaşmayacağı belirlenmiştir.…”

Section: Investigation On Manufacturability Of Bone Plates Used In Huunclassified

“…Ürünün konumlandırıldığı platformun belirli bir sıcaklığa kadar ısıtılması şeklinde gerçekleştirilen ön ısıtma işleminin, soğuma hızını kısmen azaltması nedeniyle ısıl gradyanların oluşmasını azalttığı tespit edilmiştir [11]. Kemik plakalarının vücut içerisinde farklı yükleme koşullarına maruz kaldığı dikkate alındığında; kullanılan malzemenin özelliklerinin istenen düzeyde olması ve oluşan iç kuvvetlere karşı kararlılığını muhafaza etmesi büyük önem arz etmektedir [14,15]. Bu nedenle, plakaların mekanik özelliklerinin doğru biçimde belirlenmesi ve uygun biçimde yerine tespit edilmesi operasyonun başarısı için kaçınılmazdır.…”

Section: Gi̇ri̇ş (Introduction)unclassified

“…Plakaların özellikle eğme, çekme ve yorulma dayanımlarının bilinmesi ve uygulamanın bu çerçevede gerçekleştirilmesi cerrahi operasyonun uzun vadedeki başarımını belirleyecektir. Eğme veya çekme yükü altındaki plakalarda oluşan çatlak oluşması ve ilerlemesi plakanın yorulma dayanımını doğrudan etkilemektedir [14]. Vücudun farklı bölgelerinde farklı yükleme bileşenlerinin oluşmasından dolayı kemik plakaların ön görülen bölge için tasarımlanması, uygun malzeme seçimi ve üretim yöntemi kullanılarak üretilmesi gerekmektedir.…”

Section: Gi̇ri̇ş (Introduction)unclassified

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Humerus kırıklarında kullanılan kemik plakalarının eklemeli imalat yöntemi ile üretilebilirliğinin incelenmesi

Aycan¹

2018

Gazi Üniversitesi Mühendislik-Mimarlık Fakültesi Dergisi

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The effect of building direction and preheating in additive manufacturing method  Determining of ideal production condition  Investigation of manufacturability of bone plate by additive manufacturing Figure A. Indicating of building direction; (a) Vertical, (b) Horizontal, (c) 1x45, (d) 2x45 Purpose: The aim of this study is to determine the ideal production conditions (building orientation and preheating) for bone plates in additive manufacturing method. Theory and Methods: The manufacturability of Ti6Al4V titanium alloyed bone plates used in treatment of humerus fractures by DMLS additive manufacturing method was investigated. Samples were manufactured by using same process parameters and heat treated in same conditions after production. The samples were manufactured by using four different building directions (vertical, horizontal, 1x45, 2x45) and two preheating conditions (0℃ and 200℃). After production of cylindrical samples, the stress relieving heat treatment processes were done and then they were tested in axial tensile testing and three-point bending testing (statically and dynamically). Determining ideal building direction and preheating condition by using cylindrical samples, the bone plate samples were produced and tested in four-point bending tests statically and dynamically according to the ASTM F382 in order to determine the biomechanical behavior of bone plates. Results: The orientation of samples in DMLS method did not make a significant effect on mechanical properties but the strength of samples was affected negatively with preheating process. However, it was seen that the ductility and toughness of samples increased via the preheating process. The sample manufactured with preheating in vertical direction had the highest mechanical properties when compared to the other samples. It was decided that the condition of vertical direction with preheating was accepted as an ideal condition according to the test results of cylindrical samples. Thus, the bone plates were manufactured on this condition and heat treated by same process parameters. The bone samples manufactured by additive manufacturing method has sufficient biomechanical properties comparing with conventional production methods. Conclusion: It was concluded that the bone plates manufactured by additive manufacturing method had better bending strength and fatigue behavior. They may be an alternative choice for treatments of humerus fractures in clinical applications.

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Section: Investigation On Manufacturability Of Bone Plates Used In Huunclassified

Section: Gi̇ri̇ş (Introduction)unclassified

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Humerus kırıklarında kullanılan kemik plakalarının eklemeli imalat yöntemi ile üretilebilirliğinin incelenmesi

Aycan¹

2018

Gazi Üniversitesi Mühendislik-Mimarlık Fakültesi Dergisi

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“…Additive manufacturing (AM) offers an efficient solution for the fabrication of medical fixations and implants [14]. Additive manufacturing has several advantages (see Fig.…”

Section: Introductionmentioning

confidence: 99%

A Review on Powder Bed Fusion Additive Manufacturing for Metallic Fixation Implants

Al-Tamimi

Alqahtani

Liu

et al. 2020

Virtual Prototyping &Amp; Bio Manufacturing in Medical Applications

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Bone marrow stromal cells are sensitive to discrete surface alterations in build and post‐build modifications of bioinspired Ti6Al4V 3D‐printed in vitro testing constructs

Berger

Cohen

Snyder³

et al. 2022

J Biomed Mater Res

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Current standards in bone‐facing implant fabrication by metal 3D (M3D) printing require post‐manufacturing modifications to create distinct surface properties and create implant microenvironments that promote osseointegration. However, the biological consequences of build parameters and surface modifications are not well understood. This study evaluated the relative contributions of build parameters and post‐manufacturing modification techniques to cell responses that impact osseointegration in vivo. Biomimetic testing constructs were created by using a M3D printer with standard titanium–aluminum–vanadium (Ti6Al4V) print parameters. These constructs were treated by either grit‐blasting and acid‐etching (GB + AE) or GB + AE followed by hot isostatic pressure (HIP) (GB + AE, HIP). Next, nine constructs were created by using a M3D printer with three build parameters: (1) standard, (2) increased hatch spacing, and (3) no infill, and additional contour trace. Each build type was further processed by either GB + AE, or HIP, or a combination of HIP treatment followed by GB + AE (GB + AE, HIP). Resulting constructs were assessed by SEM, micro‐CT, optical profilometry, XPS, and mechanical compression. Cellular response was determined by culturing human bone marrow stromal cells (MSCs) for 7 days. Surface topography differed depending on processing method; HIP created micro‐/nano‐ridge like structures and GB + AE created micro‐pits and nano‐scale texture. Micro‐CT showed decreases in closed pore number and closed porosity after HIP treatment in the third build parameter constructs. Compressive moduli were similar for all constructs. All constructs exhibited ability to differentiate MSCs into osteoblasts. MSCs responded best to micro−/nano‐structures created by final post‐processing by GB + AE, increasing OCN, OPG, VEGFA, latent TGFβ1, IL4, and IL10. Collectively these data demonstrate that M3D‐printed constructs can be readily manufactured with distinct architectures based on the print parameters and post‐build modifications. MSCs are sensitive to discrete surface topographical differences that may not show up in qualitative assessments of surface properties and respond by altering local factor production. These factors are vital for osseointegration after implant insertion, especially in patients with compromised bone qualities.

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Comparison of conventional reconstruction plate versus direct metal laser sintering plate: an in vitro mechanical characteristics study

Cited by 10 publications

References 25 publications

Humerus kırıklarında kullanılan kemik plakalarının eklemeli imalat yöntemi ile üretilebilirliğinin incelenmesi

Humerus kırıklarında kullanılan kemik plakalarının eklemeli imalat yöntemi ile üretilebilirliğinin incelenmesi

A Review on Powder Bed Fusion Additive Manufacturing for Metallic Fixation Implants

Bone marrow stromal cells are sensitive to discrete surface alterations in build and post‐build modifications of bioinspired Ti6Al4V 3D‐printed in vitro testing constructs

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