Comparison of conventional and simultaneous compression-ventilation cardiopulmonary resuscitation in piglets.

Hou, Shou-Hsien; Lue, Hung-Chi; Chu, Shu‐Hsun

doi:10.1253/jcj.58.426

Cited by 16 publications

(7 citation statements)

References 22 publications

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“…Another LOE 5 VF piglet study 228 demonstrated equivalent cardiac output but worsened gas exchange using a 1:1 compression-ventilation ratio (ie, simultaneous compressions and ventilations) with high airway pressures compared with conventional CPR at a 5:1 ratio.…”

Section: Compression-ventilation Ratiomentioning

confidence: 99%

Part 10: Pediatric Basic and Advanced Life Support

Kleinman

Caen

Chameides³

et al. 2010

Circulation

183

184

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Note From the Writing Group: Throughout this article, the reader will notice combinations of superscripted letters and numbers (eg, “Family Presence During ResuscitationPeds-003”). These callouts are hyperlinked to evidence-based worksheets, which were used in the development of this article. An appendix of worksheets, applicable to this article, is located at the end of the text. The worksheets are available in PDF format and are open access.

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Section: Compression-ventilation Ratiomentioning

confidence: 99%

Part 10: Pediatric Basic and Advanced Life Support

Kleinman

Caen

Chameides³

et al. 2010

Circulation

183

184

View full text Add to dashboard Cite

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“…24 Interestingly, studies in infant piglets were unable to demonstrate an increase in intrathoracic pressure or enhanced myocardial and cerebral perfusion during uninterrupted CCs. 21,28 However, our model differentiates substantially from Berkowitz et al 21 and Hou et al 28 Berkowitz and Hou delivered 60 CCs/min in addition to 60 inflations/min. Our studies used 120 CCs/min, which is twice as many as Berkowitz and Hou used in their studies.…”

Section: Discussionmentioning

confidence: 48%

“…In addition, our model used peak inflation pressures of 30 cm H 2 O in comparison with the 60 cm H 2 O in the Berkowitz and Hou studies. 21,28 The increased peak inflation pressures might have impaired blood flow. In addition, the delivered V T in our study was ≈14 mL/kg.…”

Section: Discussionmentioning

confidence: 99%

“…Berkowitz and Hou used a peak inflation pressure of 60 cm H 2 O for their rescue breaths, which potentially delivered even higher V T s and might have caused increased lung tissue injury in the experimental group in Hou's study. 28 Overall, our model uses constant peak inflation pressure of 30 cm H 2 O for the duration of the SI to passively ventilate the lung, in comparison with the Berkowitz and Hou studies, in which 60 inflations/min were delivered. The V T in our study was potentially limited to the force used to deliver CCs.…”

Section: Discussionmentioning

confidence: 99%

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Cardiopulmonary Resuscitation With Chest Compressions During Sustained Inflations

et al. 2013

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Background-Guidelines on neonatal resuscitation recommend 90 chest compressions (CCs) and 30 manual inflations (3:1) per minute in newborns. The study aimed to determine whether CC s during sustained inflations (SIs) improves the recovery of asphyxiated newborn piglets in comparison with coordinated 3:1 resuscitation. Methods and Results-Term newborn piglets (n=8/group) were anesthetized, intubated, instrumented, and exposed to 45-minute normocapnic hypoxia followed by asphyxia. Piglets were randomly assigned to receive either 3:1 resuscitation (3:1 group) or CCs during SIs (SI group) when the heart rate decreased to 25% of baseline.

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“…Priority is given to assuring adequate ventilation and avoidance of potentially harmful excessive barotrauma in children. 241 Reassess the victim after 20 cycles of compressions and ventilations (slightly longer than 1 minute) and every few minutes thereafter for any sign of resumption of spontaneous breathing or signs of circulation. The number 20 is easy to remember, so it is used to provide a guideline interval for reassessment rather than an indication of the absolute number of cycles delivered in exactly 1 minute.…”

Section: Coordination Of Compressions and Rescue Breathingmentioning

confidence: 99%

Part 9: Pediatric Basic Life Support

2000

Circulation

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• The extremely complex skills sequence for lay rescuer relief of foreign-body airway obstruction (FBAO) in the unconscious victim has been simplified. The sequence for healthcare provider relief of FBAO in the unconscious victim remains unchanged (Class IIb). IntroductionPediatric BLS refers to the provision of CPR, with no devices or with bag-mask ventilation or barrier devices, until advanced life support (ALS) can be provided. The population addressed in this chapter includes infants from birth to 1 year of age and children from 1 to 8 years of age. CPR and life support in the pediatric age group should be part of a community-wide Chain of Survival that links the child to the best hope of survival following emergencies. The Chain of Survival integrates education in prevention of cardiopulmonary arrest, BLS, early access to EMS systems prepared for children's needs, early and effective pediatric Sudden cardiopulmonary arrest in infants and children is much less common than sudden cardiac arrest in adults. 4 In contrast to cardiac arrest in adults, cardiac arrest in infants and children is rarely a sudden event, and non-cardiac causes predominate. 4 The etiology of cardiac arrest in infants and children varies by age, setting, and the underlying health of the child. For these reasons, the sequence of CPR for infants and children requires a different approach from that used for adult victims.Cardiac arrest in the under-21-year-old age group occurs most commonly at either end of the age spectrum: under 1 year of age and during the teenage years. In the newly born infant, respiratory failure is the most common cause of cardiopulmonary deterioration and arrest. During infancy the most common causes of arrest include sudden infant death syndrome (SIDS), respiratory diseases, airway obstruction (including foreign-body aspiration), submersion, sepsis, and neurological disease. [5][6][7][8][9][10][11] Beyond 1 year of age, injuries are the leading cause of death. [12][13][14] Cardiac arrest in children typically represents the terminal event of progressive shock or respiratory failure. Either shock or respiratory failure may include a compensated state from which children can rapidly deteriorate to a decompensated condition with progression to respiratory or cardiac arrest. Therefore, rescuers must detect and promptly treat early signs of respiratory and circulatory failure to prevent cardiac arrest. In children, early effective bystander CPR has been associated with successful return of spontaneous circulation and neurologically intact survival. 15,16 BLS courses should be offered to target populations such as expectant parents, child care providers, teachers, sports supervisors, and others who regularly care for children. Parents and child care providers of children with underlying conditions that predispose them to cardiopulmonary failure should be particularly targeted for these courses.These guidelines are based on a review and analysis of clinical and experimental evidence. 17 Because this evidence varies widely...

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Comparison of conventional and simultaneous compression-ventilation cardiopulmonary resuscitation in piglets.

Cited by 16 publications

References 22 publications

Part 10: Pediatric Basic and Advanced Life Support

Part 10: Pediatric Basic and Advanced Life Support

Cardiopulmonary Resuscitation With Chest Compressions During Sustained Inflations

Part 9: Pediatric Basic Life Support

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