Comparison of Contrast Media and Low-Molecular-Weight Dextran for Frequency-Domain Optical Coherence Tomography

Clinical Utility and Significance of Intravascular Ultrasound and Optical Coherence Tomography in Guiding Percutaneous Coronary Interventions

“…However, a recent study indicated that low-molecular-weight dextran can be substituted for contrast media without negatively affecting OCT coronary imaging as compared with the use of radiographic contrast media. 28 …”

High-Density Lipoprotein Cholesterol Level Is Associated With Fibrous Cap Thickness in Acute Coronary Syndrome

“…22 Fibrous cap was identified as a tissue layer that is a signalcal, Tokushima, Japan) via a guiding catheter at a rate of 2.5-4.5 ml/s using an auto injector pump (Mark V; Medrad, Warrendale, PA, USA) for both methods. 20, 21 A total of 3,000 units unfractionated heparin were given every hour during the procedure to maintain an activated clotting time >300 s. In addition to initial loading of aspirin (100 mg) and clopidogrel (300 mg) prior to PCI, the following dual antiplatelet therapy was also used: aspirin (81 mg/day) and clopidogrel (75 mg/day) after stent implantation. No glycoprotein IIb/IIIa inhibitors were used in this study because these inhibitors have not been approved in Japan.…”

Optical Coherence Tomography-Derived Anatomical Criteria for Functionally Significant Coronary Stenosis Assessed by Fractional Flow Reserve

“…12 Furthermore, FD-OCT may be able to provide better measurement of vessel dimensions than TD-OCT because its image acquisition method does not require proximal balloon occlusion. 13,23, 31 Hence, further investigations exploring the relationship between coronary dimensions assessed by FD-OCT and FFR are warranted. Our study had similar findings regarding the cutoff of percent lumen area stenosis to those of previous IVUS studies, which guarantees the accuracy of our results.…”