Comparison of contemporary invasive and non-invasive
Streptococcus pneumoniae
isolates reveals new insights into circulating anti-microbial resistance determinants
Charlie Higgs,
Lamali Sadeesh Kumar,
Kerrie Stevens
et al.
Abstract:Streptococcus pneumoniae
is a major human pathogen with a high burden of disease. Non-invasive isolates (those found in non-sterile sites) are thought to be a key source of invasive isolates (those found in sterile sites) and a reservoir of anti-microbial resistance (AMR) determinants. Despite this, pneumococcal surveillance has almost exclusively focused on invasive isolates. We aimed to compare contemporaneous invasive and non-invasive isolate populations to understand how they interact and ident… Show more
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