Comparison of concurrent imaging modalities for staging of dogs with appendicular primary bone tumours

Abstract

This study assessed the use of whole body computed tomography (CT) for the evaluation of metastasis in dogs with primary appendicular bone tumours compared to long bone survey radiography, bone scintigraphy and thoracic radiographs. Fifteen dogs were included in this pilot study. A construct reference standard was used for detection of bone metastasis, and negative thoracic radiographs were compared against CT. Definitive lesions were only identified on bone scintigraphy. Not all lesions agreed with the construct reference standard. No definitive lesions were identified on survey radiographs or CT. Lesions were identified on thoracic CT that were not visible radiographically. Equivocal ground glass pulmonary lesions progressed in three of four cases. Whole body CT was not a suitable alternative to bone scintigraphy; however, it was useful as an adjunctive diagnostic modality. Pulmonary lesions were visible on CT that were not seen radiographically and ground glass pulmonary lesions in dogs should be considered suspicious for metastasis.

Effect of surgical site infection on survival after limb amputation in the curative‐intent treatment of canine appendicular osteosarcoma: a Veterinary Society of Surgical Oncology retrospective study

“…Three‐view thoracic radiography was the only diagnostic test to evaluate for metastatic disease in 110 (73.8%) of the cases in this study. Thoracic CT and nuclear scintigraphy are more sensitive for detecting metastatic disease, but their use can be limited by institutional availability and cost . Therefore, the potential for undocumented metastatic disease at the time of amputation in at least 1 case cannot be excluded.…”

“…Thoracic CT and nuclear scintigraphy are more sensitive for detecting metastatic disease, but their use can be limited by institutional availability and cost. [31][32][33][34] Therefore, the potential for undocumented metastatic disease at the time of amputation in at least 1 case cannot be excluded. Chemotherapy protocols also varied by institutions.…”

Prevalence of pulmonary nodules in dogs with malignant neoplasia as determined by CT

“…Computed tomography is a more sensitive method for detection of pulmonary nodules than thoracic radiography . In one study, only 10% of pulmonary nodules detected on CT could be identified on thoracic radiographs .…”

Ischiectomy With Limb Preservation for a Dog With Ischial Chondrosarcoma: Case Report and Surgical Technique

“…Based on our previous work staging osteosarcoma, bone scan and CT of the lungs is recommended. 10 We recommend local staging with CT and 3-dimensional reconstruction for surgical planning of the margins of excision, that is, to determine if complete tumor resection is possible with ischiectomy or if hemipelvectomy with limb amputation is necessary.…”