Comparison of Clinical Features and Serum Parameters of Culture-Positive Children with Culture-Negative Children in Septic Arthritis and Acute Osteomyelitis

Özcan, Çağrı; Çamur, Savaş; Shatat, K M I; Kemah, Bahattin; Söylemez, Mehmet Salih; Sağlam, Necdet

doi:10.55095/achot2021/022

Cited by 2 publications

(1 citation statement)

References 21 publications

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“…When osteomyelitis is suspected based on history and physical examination, blood investigations such as white blood cell count (WCC), C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR) along with imaging studies are performed; however, a definitive diagnosis usually requires culture of the pathogen from tissue samples 3,6,7 . The usefulness of imaging studies such as radiography, magnetic resonance imaging (MRI), computed tomography, bone scintigraphy, and ultrasound has been reported, but there is limited evidence for the requirement of imaging studies in the diagnosis and treatment of acute osteomyelitis 1,3 .…”

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Ultrasound-Guided Needle Aspiration of Subperiosteal Abscess in a Child with Acute Osteomyelitis of the Fibula

Kanamoto

Mazuka

2022

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Case: An 8-year-old boy with left lateral ankle pain was diagnosed with acute osteomyelitis after methicillinsusceptible Staphylococcus aureus was identified in a subperiosteal abscess in the distal fibula that had been aspirated using an ultrasound-guided needle. Symptoms improved after 2 weeks of intravenous and 4 weeks of oral antimicrobial therapy; no additional treatment was required. No growth retardation or sequelae were observed at the 6-year follow-up. Conclusions:In acute osteomyelitis, the identification of subperiosteal abscess is key for early diagnosis. Ultrasound evaluation of the distal fibula should also be considered in the diagnosis of lateral ankle pain in children.Disclosure: The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article (http://links.lww.com/JBJSCC/B920).

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confidence: 99%

Ultrasound-Guided Needle Aspiration of Subperiosteal Abscess in a Child with Acute Osteomyelitis of the Fibula

Kanamoto

Mazuka

2022

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Risk Factors and Clinical Features of Septic Arthritis in Children: A Systematic Review and Meta-Analysis

Hutaif

2023

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Background: Septic arthritis is a bacterial infection of the joint space that can cause permanent disability or death in children if not treated promptly. We conducted a systematic review and meta-analysis of studies published from 1980 to December 2022 to synthesize the evidence on risk factors and clinical features of septic arthritis in children. Methods: We searched PubMed, Embase, and Cochrane Library databases using the terms “septic arthritis”, “children”, “risk factors”, and “clinical features”. We included prospective cohort studies or randomized trials that reported on these outcomes. We assessed the quality of the included studies using the Cochrane risk of bias tool or the Newcastle-Ottawa scale. We pooled the results using random-effects models and calculated odds ratios (ORs) or mean differences (MDs) with 95% confidence intervals (CIs). Results: We included 42 studies with a total of 6,120 children. Risk factors for septic arthritis included age younger than 3 years (OR 2.54, 95% CI 1.87-3.46), male sex (OR 1.32, 95% CI 1.14-1.53), previous joint problems or surgery (OR 2.19, 95% CI 1.50-3.20), immunodeficiency (OR 2.76, 95% CI 1.86-4.10), and recent infection or injury (OR 2.45, 95% CI 1.72-3.49). Clinical features varied but commonly included fever (OR 5.67, 95% CI 3.66-8.79), joint pain (OR 9.23, 95% CI 5.97-14.28), swelling (OR 8.41, 95% CI 5.44-13.01), and reduced movement (OR 10.12, 95% CI 6.55-15.65). The knee was the most frequently affected joint (40%), followed by the hip (28%) and ankle (11%). Staphylococcus aureus was the most common cause of infection (40%), followed by Streptococcus pyogenes (12%) and Kingella kingae (11%). Conclusions: This review provides a comprehensive summary of risk factors and clinical features of septic arthritis in children, which can facilitate early diagnosis and treatment to prevent joint damage and systemic complications.

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Comparison of Clinical Features and Serum Parameters of Culture-Positive Children with Culture-Negative Children in Septic Arthritis and Acute Osteomyelitis

Cited by 2 publications

References 21 publications

Ultrasound-Guided Needle Aspiration of Subperiosteal Abscess in a Child with Acute Osteomyelitis of the Fibula

Ultrasound-Guided Needle Aspiration of Subperiosteal Abscess in a Child with Acute Osteomyelitis of the Fibula

Risk Factors and Clinical Features of Septic Arthritis in Children: A Systematic Review and Meta-Analysis

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