Comparison of clinical features and health manifestations in lean vs. obese Indian women with polycystic ovarian syndrome

Ghongane

et al. 2013

Indian J Endocr Metab

111

Background:Polycystic ovary syndrome (PCOS) is common diagnosis in women presenting with infertility. All the dimensions of PCOS have not been completely explored. Many studies have tried to characterize the exact presentation of the disease. In this study we studied clinical features of PCOS in Indian women to characterize different phenotypes of this syndrome. Prevalence of acanthosis nigricans (AN) as surrogate marker of insulin resistance, obesity, hirsutism and hypothyroidism in PCOS women have been simultaneously studied.Materials and Methods:Present work is a non comparative cross-sectional open label study carried out over a period of 18 months in an endocrinology hospital in western Maharashtra, India.Results and Conclusion:Authors conclude that PCOS occurs both in obese and non-obese women; AN and hirsutism occur in equal proportion of patients. AN is correlated with obesity. Hormonal dysfunctions in PCOS manifested together or independently. PCOS women can be sub grouped based on clinical features suggestive of endocrinological malfunctions and can be investigated accordingly for selection of appropriate treatment modalities.

Section: Discussionsupporting

confidence: 54%

“…The authors have reported prevalence of menstrual irregularities as 79.2% vs. 44% in obese vs. non-obese women. [11] In the present study, we are reporting the prevalence of oligomenorrhea as 66.67% in obese and 60% in non-obese women. In the present study, 44.68% married PCOS women complained of infertility [Table 3].…”

Section: Discussionmentioning

confidence: 71%

Clinical characteristics of polycystic ovary syndrome in Indian women

Ghongane

et al. 2013

Indian J Endocr Metab

111

Indian Dermatol Online J

“…revealed the prevalence rate of obesity to be 37.5%. [13] Lim et al . in a systemic review and meta-analysis concluded that women with PCOS had a greater risk of overweight, obesity, and central obesity.…”

Section: Discussionmentioning

confidence: 99%

Cutaneous manifestations of polycystic ovary syndrome: A cross-sectional clinical study

Keen

Shah

Sheikh

2017

Background:Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women, affecting 5–10% of reproductive-aged women. The dermatologic manifestations of hyperandrogenism, chiefly hirsutism, acne vulgaris, androgenic alopecia, and acanthosis nigricans, are among the cardinal manifestations of PCOS.Aim:To study the incidence and prevalence of various cutaneous manifestations in patients with PCOS and to correlate these skin manifestations with hormonal changes.Settings and Design:This study was conducted at a dermatology centre over a period of 1 year from November 2012 to 2013.Materials and Methods:The present study included 100 women diagnosed to have PCOS. Hormonal analysis as well as radiological assessment was done in all the cases. Cutaneous manifestations were ascertained and inferences were drawn.Statistical Analysis:Statistical analysis was carried out by the Chi-square test and independent samples t-test. Statistical significance was determined at a level of P < 0.05.Results:In our study, the prevalence of hirsutism, acne, female pattern hair loss, acanthosis nigricans, seborrhea, striae and acrochordons was 78%, 48%, 31%, 30%, 29%, 13%, and 9%, respectively.Conclusion:Dermatologic manifestations of PCOS play a significant role in making the diagnosis and constitute a substantial portion of the symptoms experienced by women with this syndrome.

Obs Gyne Reivew J Obstet Gynecol

“…The prevalence of obesity and overweight women in the present study was 30% and 40%, respectively. A study conducted by Majumdar et al revealed the prevalence rate of obesity to be 37.5% [11]. Ramanand et al reported irregular cycles in 100% of their study participants, whereas infertility was present in 21% [12].…”

Section: Discussionmentioning

confidence: 90%

Clinical presentations of polycystic ovary syndrome in a tertiary care centre of southern Rajasthan, India

Barya

Babel

2019

Background: Polycystic ovarian syndrome (PCOS) is a reproductive-endocrine-metabolic disorder that involves multiple medical specialities. It can affect the entire lifespan of a woman. This disorder often strikes young girls at the time when they are stepping into the newer horizon of youth. Considering the symptoms of PCOS such as obesity, infertility, hirsutism, baldness etc., PCOS can be termed as "Silent Killer" of a woman's womanhood. Material and Methods: This observational study was carried out from Jan. 2016 to Sept. 2019 in Ananta Institute of Medical Sciences and Research Centre. A total of 100 newly diagnosed post-pubertal PCOS patients consulting gynaecology and dermatology department were studied. Statistical analysis was carried out by the Chi-square test and independent samples t-test. Statistical significance was determined at a level of P< 0.05. Results: Authors concluded that PCOS can occur in both obese and non-obese women with high prevalence of cutaneous manifestations. Conclusion: PCOS is a public health issue of great concern and is well said to be a hidden epidemic. It represents an Iceberg with multiple tips and widening base. The dermatologic manifestations of PCOS play a significant role in diagnosis. Success in the effective management of women with PCOS is through a trans-disciplinary integrative and synchronized clinical care by the gynecologist, endocrinologist, dermatologist, nutritionist, and physical trainer.