2021
DOI: 10.3389/fmed.2021.733999
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Comparison of Clinical Characteristics for Distinguishing COVID-19 From Influenza During the Early Stages in Guangdong, China

Abstract: Background: To explore the differences in clinical manifestations and infection marker determination for early diagnosis of coronavirus disease-2019 (COVID-19) and influenza (A and B).Methods: A hospital-based retrospective cohort study was designed. Patients with COVID-19 and inpatients with influenza at a sentinel surveillance hospital were recruited. Demographic data, medical history, laboratory findings, and radiographic characteristics were summarized and compared between the two groups. The chi-square te… Show more

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Cited by 2 publications
(4 citation statements)
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“…At the beginning of the outbreak of COVID-19, the search volume for "influenza" increased rapidly, reaching an unprecedented peak. Therefore, we speculate that the outbreak time of the epidemic is the season of frequent influenza, and the symptoms of patients with new coronavirus are like influenza [7][8][9][10][11]. It is difficult for the public to distinguish between the two, coupled with the fear of the epidemic, which has led to a surge in a public search for "influenza".…”
Section: Discussionmentioning
confidence: 99%
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“…At the beginning of the outbreak of COVID-19, the search volume for "influenza" increased rapidly, reaching an unprecedented peak. Therefore, we speculate that the outbreak time of the epidemic is the season of frequent influenza, and the symptoms of patients with new coronavirus are like influenza [7][8][9][10][11]. It is difficult for the public to distinguish between the two, coupled with the fear of the epidemic, which has led to a surge in a public search for "influenza".…”
Section: Discussionmentioning
confidence: 99%
“…While viral competition and increased vaccination may have contributed, we propose that the most influential process in suppressing the influenza epidemic of 2020-2021 were the significant behavioral interventions in place due to the COVID-19 pandemic. Nonpharmaceutical interventions such as closures of schools and non-essential businesses, telework, restriction on gathering size [11], and mask-wearing have been key public health tools for limiting the impact of the COVID-19 pandemic [19,20].…”
Section: Discussionmentioning
confidence: 99%
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“…La caracterización en este estudio de la enfermedad COVID-19 mostró algunos hallazgos que pueden orientar al médico primario a la diferenciación con la influenza en un futuro. Por ejemplo, la influenza muestra mayor prevalencia de fiebre alta, tos y expectoración y, en menor grado astenia [38,39]. En tanto, en los hallazgos de esta población muestra que en todos los grupos etarios predomina astenia, anosmia, cefalea y fiebre, y no los síntomas respiratorios.…”
Section: Discussionunclassified