Comparison of Clinical and Radiographic Success between MTA and Biodentine in Pulpotomy of Primary Mandibular Second Molars with Irreversible Pulpitis: A Randomized Double-Blind Clinical Trial

Abstract

Introduction. Among the new therapeutic materials, MTA and Biodentine are recommended for pulpotomy and sealing the pulp. Considering the similar characteristics of these two materials and considering that their effects on the treatment of primary second molars with irreversible pulpitis have not been compared properly, this study aimed to compare clinical and radiographic success between MTA and Biodentine in pulpotomy of primary mandibular second molars with irreversible pulpitis. Materials and Methods. This study was conducted as a randomized double-blind clinical trial. Participants were selected according to inclusion criteria and 52 samples were randomly selected using random numbers table in group A. Then, patients in the next group B were matched with the first group in terms of age range and sex. In group A, the remaining pulp was covered with 2 mm MTA+ and in group B with 3 mm Biodentine. Participants were called for clinical evaluation every three months for 12 months (long-term follow-up). Radiographic evaluations were in the sixth and twelfth months. Results. Fischer’s exact test showed that there was no significant difference between MTA and Biodentine in terms of clinical and radiographic success rates ( P value = 1). According to the results of the Kaplan–Meier test, the survival rate in both pulp treatment methods was similar in symptomatic teeth. Conclusions. The results of this study showed that Biodentine properties are similar to MTA, and both materials show high clinical and radiographic success rates in long-term follow-up.

Treatment Outcomes of Pulpotomy in Primary Teeth with Irreversible Pulpitis: A Systematic Review and Meta-Analysis

“…Overall, the current review comprised a total of 266 primary teeth treated with pulpotomy. Two of the studies were conducted in Iran [7,29], followed by two in Syria [30,31], and one in China [32]. Most of the primary articles were published in 2022, consisting of two randomised clinical studies [7,30], and the remaining three were non-randomised clinical studies.…”

“…Two of the studies were conducted in Iran [7,29], followed by two in Syria [30,31], and one in China [32]. Most of the primary articles were published in 2022, consisting of two randomised clinical studies [7,30], and the remaining three were non-randomised clinical studies. Among the three non-randomised studies, two were prospective cohort studies [29,31], and one was a retrospective cohort study [32].…”

“…For randomised clinical studies, all domains assessed using the RoB 2 tool were determined to have a "low risk of bias". In general, three studies were classified as "low risk of bias" [7,29,30], one study was rated as "moderate risk of bias" [32], with another study rated as "high risk of bias" [31]. Additionally, two of the included studies were ranked as Level 2 evidence [7,30], while the other three studies were ranked as Level 3 evidence [29,31,32], according to the OCEBM criteria (Table 2).…”

“…The primary objective of treating irreversible pulpitis is to alleviate pain and prevent further infection spread while maintaining the integrity and function of the affected tooth [7]. Traditionally, the treatment of choice for irreversible pulpitis has been pulpectomy, which involves the complete removal of the infected pulp tissue or extraction [8].…”

Role of biodentine in endodontics: a bibliometric and scientometric analysis

“…The powder consists of minerals such as zirconium oxide, calcium carbonate, dicalcium and tricalcium silicate. In addition to the water-soluble polymer that serves as a reductant, the liquid also contains an aqueous solution of calcium chloride [9][10][11][12] . After preparation, within 10-12 minutes, the substance will have hardened.…”