Comparison of Clinical and Genetic Characteristics Between Younger and Older Lung Cancer Patients

Candal-Pedreira, Cristina; Ruano-Ravina, Alberto; Calvo de Juan, Virginia; Cobo, Manuel; Trigo, José Manuel; Rodríguez-Abreu, Delvys; Estival, Anna; Carcereny, Enric; Cucurull, Marc; López Castro, Rafael; Medina, Andrea; García Campelo, Rosario; Cordeiro González, Patricia; Sánchez-Gastaldo, Amparo; Bosch-Barrera, Joaquim; Massutí, Bartomeu; Dómine, Manuel; Camps, Carlos; Ortega, Ana Laura; Sánchez-Hernández, Alfredo; Guirado Risueño, María; del Barco Morillo, Edel; Garrido Fernández, Alberto; Provencio, Mariano

doi:10.1016/j.arbres.2023.12.005

Archivos de Bronconeumología

2024

DOI: 10.1016/j.arbres.2023.12.005

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Comparison of Clinical and Genetic Characteristics Between Younger and Older Lung Cancer Patients

Cristina Candal-Pedreira,

Alberto Ruano-Ravina,

Virginia Calvo de Juan

et al.

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Tackling Non–Small Cell Lung Cancer in Young Adults: From Risk Factors and Genetic Susceptibility to Lung Cancer Profile and Outcomes

Laguna,

Tagliamento,

Lambertini

et al. 2024

Am Soc Clin Oncol Educ Book

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Lung cancer has traditionally been associated with advanced age; however, its increasing incidence among young adults raises concerning questions regarding its etiology and unique considerations for this population. In contrast to the older population, the onset of lung cancer at younger age may be attributed to a complex interplay of incompletely understood individual susceptibility and prevalent environmental risk factors beyond tobacco smoke exposure, such as radon gas and air pollution, which are widespread globally. Consequently, this leads to distinct clinical and molecular profiles, requiring a tailored approach. Furthermore, a diagnosis of cancer represents a threatening event during the prime years of a young person's life, prompting concern about career development, social aspects, fertility aspirations, and physical independence. This poses significant additional challenges for health care professionals in a field that remains underexplored. This comprehensive review recognizes lung cancer in young adults as a distinct entity, exploring its clinical and molecular characteristics, diverse predisposing factors, and priorities in terms of quality of life, with the aim of providing practical support to oncologists and enhancing our understanding of this under-researched population.

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Tackling Non–Small Cell Lung Cancer in Young Adults: From Risk Factors and Genetic Susceptibility to Lung Cancer Profile and Outcomes

Laguna,

Tagliamento,

Lambertini

et al. 2024

Am Soc Clin Oncol Educ Book

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show abstract

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Comparison of Clinical and Genetic Characteristics Between Younger and Older Lung Cancer Patients

Cited by 1 publication

References 24 publications

Tackling Non–Small Cell Lung Cancer in Young Adults: From Risk Factors and Genetic Susceptibility to Lung Cancer Profile and Outcomes

Tackling Non–Small Cell Lung Cancer in Young Adults: From Risk Factors and Genetic Susceptibility to Lung Cancer Profile and Outcomes

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