Comparison of clinical and biochemical profile of obese and nonobese children

Patil, Lingaraja Gowda C.; Srinivas, Sowmya

doi:10.18203/2349-3291.ijcp20185206

Cited by 3 publications

(1 citation statement)

References 10 publications

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“…This study was done on 100 subjects among which 59% (n=59) were overweight and 41% (n=41) were obese subjects similar to a study done by Kotian et al in South India and Patil LGC et al in Karnataka 2018. [6,7] Obesity was predominant in male than female children (65%,n=65 vs. 35%,n=35). Similar results were shown in a study done by Verma et al in West Delhi.…”

Section: Discussionmentioning

confidence: 98%

Predictors of Overweight and Obesity among Children in Haldwani, Uttarakhand

Choudhary

Singh

Bathla

et al. 2020

AJCPN

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Background: Obesity has become a concerning pediatric health problem in the modern era with lifestyle changes in globalization, economic development and easy access to technology. The aim of the study is to study the anthropometric profile of overweight and obesity and its associated risk factors. Subjects and Methods: A school-based cross-sectional study was implemented among randomly chosen 100 obese and overweight children aged between 10-18 years over 15 months. Data was collected using a structured self-administered questionnaire and anthropometry was done and categorized as overweight and obese as per WHO BMI- age cutoff. Results: 41 % (n=41) were obese and 59% (n=59) were overweight. 65 % (n=65) were males. In all the age groups the mean weight of males was more except in the age group 10-12 years. Mean weight (64.39 12.88 kg) and mean BMI (26.04 1.95 kg/m2) of obese children is significantly higher than mean weight (56.73 9.76 kg) and mean BMI (23.25 1.98 kg/m2) of overweight children respectively. Risk factors like skipping breakfast (p= 0.034), calorie excess (p= 0.032), junk food intake more than once (p=0.008) and junk food daily (p=0.036) were found to be significantly associated with childhood obesity. Conclusion: Sensitization of parents and teachers with school-based programs like active participation in sports, regular anthropometric examinations of students are important measures that can be taken to curb this rising problem.

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Section: Discussionmentioning

confidence: 98%

Predictors of Overweight and Obesity among Children in Haldwani, Uttarakhand

Choudhary

Singh

Bathla

et al. 2020

AJCPN

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Childhood obesity accelerates biological ageing: is oxidative stress a link?

Subošić,

Zdravković,

Ješić

et al. 2024

Br J Nutr

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Obesity is multifactorial pathophysiological condition with an imbalance in biochemical, immunochemical, redox status and genetic parameters values. We aimed estimate connection between relative leukocyte telomere lengths (rLRL) - biomarker of cellular aging with metabolic and redox status biomarkers values in a group of obese and lean children. The study includes 110 obese and 42 lean children and adolescents, both genders. The results suggested that rLTL are significantly shorter in obese, compared to lean group (p<0,01). Negative correlation of rLTL with total oxidant status, TOS (Spearman’s ρ = –0.365, p<0.001) as well as with C reactive protein (Spearman’s ρ= –0,363, p<0.001) were observed. Principal component analysis (PCA) extracted three distinct factors (i.e. principal components) entitled as: prooxidant factor with 35% of total variability; antioxidant factor with 30% of total variability and lipid antioxidant – biological ageing factor with 12% of the total variability. The most important predictor of body mass index (BMI) >30kg/m2 according to logistic regression analysis was PCA derived antioxidant factor’s score (OR: 1.66, 95th Cl: 1.05-2.6, p=0.029). PCA analysis confirmed oxidative stress importance in biological ageing caused by obesity and its multiple consequences related to prooxidants augmentation and antioxidants exhaustion and gave us clear signs of disturbed cellular homeostasis deepness, even before any overt disease occurrence.

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Retrospective Study of Biochemical Markers and Risk Factors in Obese and Non-Obese Adolescence

Jayarajan¹,

Abirami²

2022

jbarbiomed

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Obesity is a chronic disease defined by an excessive accumulation of body fat that represents health risks, being considered now a days the major public health problem worldwide. Obesity is characterized as a low-grade inflammatory disease due to the variety of pro-inflammatory adipokines secreted by adipose tissue, especially visceral adipose tissue. This inflammation is characterized by macrophage infiltration and expression of inflammatory adipokines, which are related to insulin resistance, blood pressure, and vascular endothelium alterations. These alterations are closely related to development and progression of diabetes and cardiovascular disease, including paediatric patients. Obesity considered now as one among the major global issue affecting young adults. Rapid changes in sedentary lifestyle choices were the risk factors for obesity including unhealthy diet patterns, expending time in front of TV and lacking physical activity etc. The present study aimed for correlating the risk factors of obesity with healthy groups among the adolescent population. And the result were recorded with significant level of elevation in most of the parameters in cases than control and the significance was represented as student’s test. (p<0.001).

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Comparison of clinical and biochemical profile of obese and nonobese children

Cited by 3 publications

References 10 publications

Predictors of Overweight and Obesity among Children in Haldwani, Uttarakhand

Predictors of Overweight and Obesity among Children in Haldwani, Uttarakhand

Childhood obesity accelerates biological ageing: is oxidative stress a link?

Retrospective Study of Biochemical Markers and Risk Factors in Obese and Non-Obese Adolescence

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