Comparison of Characteristics of Neuropathic and Non-neuropathic Pruritus to Develop a Tool for the Diagnosis of Neuropathic Pruritus: The NP5

Huguen, J.; Brenaut, E.; Clerc, Christian; Poizeau, Florence; Marcorelles, Pascale; Quéreux, G.; Dupuy, Alain; Miséry, Laurent

doi:10.3389/fmed.2019.00079

Cited by 12 publications

(10 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As a result, the Neuropathic Pruritus 5 (NP5) score was suggested based on the 5 independent factors for neuropathic itch. The presence of two out of five criteria yield a sensitivity of 76% and a specificity of 77% in discriminating neuropathic from non-neuropathic itch ( 33 ). For SFN a patient oriented survey including a question on itchy skin is in development ( 34 ).…”

Section: Standardized Questionnairesmentioning

confidence: 99%

Neuropathic Itch: Routes to Clinical Diagnosis

et al. 2021

View full text Add to dashboard Cite

Neuropathic itch occurs due to damage of neurons of the peripheral or central nervous system. Several entities, including metabolic, neurodegenerative, orthopedic, infectious, autoimmune, malignant, and iatrogenic conditions, may affect the somatosensory system and induce neuropathic itch. Due to the complex nature of neuropathic itch, particularly concerning its clinical presentation and possible etiological factors, diagnostic work-up of this condition is challenging. A detailed medical history, especially in regard to the itch, and a comprehensive physical examination are relevant to detect characteristic signs and symptoms of neuropathic itch and to rule out other possible causes for chronic itch. Complementary diagnostic exams, especially laboratory tests, determination of the intraepidermal nerve fiber density via a skin biopsy and radiological examinations may be indicated to confirm the diagnosis of neuropathic itch and to identify underlying etiological factors. Functional assessments such as quantitative sensory testing, nerve conduction studies, evoked potentials, or microneurography may be considered in particular cases. This review article provides a comprehensive overview of the diagnostic work-up recommended for patients with neuropathic itch.

show abstract

Section: Standardized Questionnairesmentioning

confidence: 99%

Neuropathic Itch: Routes to Clinical Diagnosis

et al. 2021

View full text Add to dashboard Cite

show abstract

“…During detailed analysis of itching, not only an assessment of its localization, intensity, frequency, duration, provoking or relieving factors may be advisable, but also a description of the itch associated feelings (tickling, stinging, stabbing, pinching, burning, etc.) [ 48 , 49 ].…”

Section: Resultsmentioning

confidence: 99%

Treatment Algorithm for Cancerous Wounds: A Systematic Review

Furka

Simkó

Kostyál

et al. 2022

Cancers

View full text Add to dashboard Cite

Background: In advanced cancer stage the incidence of cancerous wounds is about 5%, and the estimated life expectancy is not more than 6 to 12 months. Without interdisciplinary and individualized treatment strategy, symptoms progress, and adversely influence quality of life. Methods: Authors collected different treatment algorithms for cancerous wound published by wide scale of medical expertise, and summarized surgical, oncological, radiation oncological, nursing and palliative care aspects based on radiological information. Results: Interdisciplinary approach with continuous consultation between various specialists can solve or ease the hopeless cases. Conclusions: This distressing condition needs a comprehensive treatment solution to alleviate severe symptoms. Non-healing fungating wounds without effective therapy are severe socio-economic burden for all participants, including patients, caregivers, and health services. In this paper authors collected recommendations for further guideline that is essential in the near future.

show abstract

“…Moreover, patients describing burning or stinging sensations suggest a neuropathic component of pain associated with neurogenic inflammation. Furthermore, sensations such as tingling or burning can be associated with neuropathic pruritus [22, 23].…”

Section: Discussionmentioning

confidence: 99%

Pruritus, Pain, and Depression Associated with the Most Common Skin Diseases: Data from the French Study “Objectifs Peau”

et al. 2021

Self Cite

View full text Add to dashboard Cite

Background: The prevalence and impact of pruritus, pain, and other sensory symptoms in skin diseases are poorly known. Objective: To assess the frequency of these symptoms with dermatoses and their association with depression using data from the “Objectifs Peau” survey. Methods: A representative sample of 20,012 French individuals was created using the usual quota method. Results: When patients suffered from both pruritus and skin pain, they had a higher relative risk of psychological suffering (2.9) than those who suffered only from pruritus (1.4) or skin pain (1.2). Pruritus was reported in 48.55% of patients with acne, 43.24% with mycoses, 44.35% with warts, and 36.51% with rosacea. For skin pain, the results were 11.22%, 27.59%, and 16.13% for atopic dermatitis, acne, and warts, respectively. Other unpleasant sensations, such as tingling or burning, were also frequently reported. Conclusion: Pruritus, pain, or other sensory symptoms were found to be common not only in classic pruritic skin diseases but also in acne, rosacea, or warts. The association of pruritus and pain dramatically increased psychological suffering. These symptoms must be systematically searched for in patients, especially since new therapeutic possibilities are emerging for the symptomatic treatment of pruritus.

show abstract

Comparison of Characteristics of Neuropathic and Non-neuropathic Pruritus to Develop a Tool for the Diagnosis of Neuropathic Pruritus: The NP5

Cited by 12 publications

References 20 publications

Neuropathic Itch: Routes to Clinical Diagnosis

Neuropathic Itch: Routes to Clinical Diagnosis

Treatment Algorithm for Cancerous Wounds: A Systematic Review

Pruritus, Pain, and Depression Associated with the Most Common Skin Diseases: Data from the French Study “Objectifs Peau”

Contact Info

Product

Resources

About