Comparison of cervicovaginal Pap-smear results with clinical parameters

Erdem, Havva; Şahiner, Cem; Yıldırım, Ümran; Köse, Seyit Ali; Karataş, Ahmet; Uzunlar, Ali Kemal; Kadıoğlu, Nilüfer; Şipal, Sare

doi:10.5505/jkartaltr.2011.40469

J Kartal TR

2011

DOI: 10.5505/jkartaltr.2011.40469

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Comparison of cervicovaginal Pap-smear results with clinical parameters

Havva Erdem¹,

Cem Şahiner²,

Ümran Yıldırım³

et al.

Abstract: ÖzetAmaç: Serviks kanseri, gelişmekte olan ülkelerde kadınlarda kansere bağlı ölümlerin önde gelen nedenidir. Bu makalede, bölümümüze başvuran kadın hastaların klinik parametrelerini değerlendirerek, smear sonuçları ile karşılaştırmak istedik. Gereç ve Yöntem:Kadın doğum polikliniğimize 2010-2011 yılı arası başvuran 1101 kadının Bethesda sistemine göre değerlendirilen smear sonuçları, retrospektif klinik verilerle değerlendirildi. Bulgular:Yaş arttıkça enflamasyon tanısının normal izlenmesine oranla anlamlı ol… Show more

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Cited by 3 publications

(9 citation statements)

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“…A s of 2018, cervical carcinoma was the fourth most common type of cancer among women in the world, and also the eighth most common cancer in the society [1] , whereas in Turkey, it is the eighth most common and mortal type of cancer both among women and in the society [2] .…”

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confidence: 99%

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confidence: 99%

“…The incidence of cervical carcinoma is much higher in developing countries due to the limited utilization of cervical Pap smear screening tests [2][3][4][5] . Cervical carcinoma develops at the end of a long precancerous stage (10-40 years) [2,[5][6][7][8] . Thus, this rate has been decreasing in devel-oped countries thanks to extensive and systematic cervical smear screening programs [2,[5][6][7][8] .…”

mentioning

confidence: 99%

“…Cervical carcinoma develops at the end of a long precancerous stage (10-40 years) [2,[5][6][7][8] . Thus, this rate has been decreasing in devel-oped countries thanks to extensive and systematic cervical smear screening programs [2,[5][6][7][8] . Nowadays, although false-negative rates vary between 2% and 50% in different centers, the Pap smear cervical cancer screening test is still accepted as the most effective method to detect precancerous lesions [2] .…”

mentioning

confidence: 99%

“…Thus, this rate has been decreasing in devel-oped countries thanks to extensive and systematic cervical smear screening programs [2,[5][6][7][8] . Nowadays, although false-negative rates vary between 2% and 50% in different centers, the Pap smear cervical cancer screening test is still accepted as the most effective method to detect precancerous lesions [2] . Cervical cancer screening with Pap smear is a cheap and easily applicable test [8] .…”

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confidence: 99%

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Diagnostic Distribution of Cervicovaginal Smear in Bursa and Its Surrounding

Erkinüresin¹

2019

Haydarpasa Numune Med J

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Introduction: In this study, our aim was to analyze Pap smear cervical cancer screening results at our hospital. We also sought to compare our ASC/SIL rate with the relevant studies in the literature, which is one of the quality standard criteria for the pathology laboratory. Methods: In our study, digital reports of 6902 cases diagnosed according to the Bethesda Reporting System for Pap cervical cancer screening and other medical indications in the pathology department of our hospital between 1st January 2018 and 31st December 2018 were reviewed retrospectively. Results: When 6902 cervicovaginal smear cases were analyzed concerning epithelial abnormality, 6528 cases (94.6%) were reported as NILM, and seven cases (0.1%) were reported as an inadequate smear. Epithelial abnormality was detected in the remaining 367 (5.3%) cases. Out of 367 cases,279 (4.0%) of them were reported as ASC-US;42 cases (0.6%) as AGC-NOS;24 cases (0.3%) as LSIL;12 cases (0.2%) as ASC-H, seven cases (0.1%) as HSIL; one case (0.0%) as LSIL and AGC-NOS; one case (0.0%) as ASC-H and AGC-NOS and one case (0.0%) as squamous cell carcinoma (SCC). The ASC/SIL rate of our laboratory for the year 2018 was 9.125. Discussion and Conclusion: Our SCC rate was 0.02%, which was the second-lowest rate in the relevant literature. The reason for this may be the success of the cervicovaginal Pap smear screening program performed in our region. Our inadequate cervicovaginal smear rate concerning assessment was the lowest rate in the literature. Our ASC/SIL rate was 9.125, and this was the third highest ASC/SIL rate in the literature. The reason for our laboratory's 2018 ASC/SIL rate of 9.125 may be the concern of some of our pathologists of false-negative reports. We detected various differences between epithelial abnormality and infection prevalence in the cervicovaginal smears in our region and epithelial abnormality and infection prevalence in different regions of the world. Intra-departmental case presentations and in-service training could be organized to keep the ASC/SIL rate in the pathology laboratory under three. At the same time, pathologists' quarterly ASC/SIL rates could be calculated and reported to the pathologists.

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confidence: 99%

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confidence: 99%

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confidence: 99%

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confidence: 99%

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confidence: 99%

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Diagnostic Distribution of Cervicovaginal Smear in Bursa and Its Surrounding

Erkinüresin¹

2019

Haydarpasa Numune Med J

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Comparison of Cervical Smear and Biopsy Results

Harmankaya

2020

Journal of Contemporary Medicine

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Amaç: Serviks kanseri 20.yy başlarına kadar kadın genital organ kanserleri içinde ön sıralarda iken 1950'lerden sonra servikal kanser taramasının yaygınlaşmasına bağlı olarak insidans ve serviks kanserinden ölüm %50 oranında azalmıştır. Servik kanseri gelişiminde insan papilloma virüsü ile enfeksiyon en önemli etkendir. Servikal yayma ile tarama özellikle gelişmiş ülkelerde serviks kanseri ve öncül lezyonlarının erken tanısı için kullanılan önemli bir yöntemdir. Geraç ve Yöntem: Selçuk Üniversitesi Tıp Fakültesi Hastanesi Tıbbi Patoloji laboratuarında 2010-2018 yılları arasında incelenen ve raporlanan, öncesinde smear sonucu olan ve servikal biyopsi yapılan 223 hastanın sonuçları karşılaştırıldı. Bulgular: 223 hastanın yaş ortalaması 45 (26-83) dir. Biyopsi sonuçları 173 (%78) hastada kronik inflamasyon, 15 (%7) hastada düşük dereceli skuamöz intraepitelyal lezyon “HPV veya hafif displazi veya CIN 1, 21 (%9) hastada yüksek dereceli skuamöz intraepitelyal lezyon “Orta derecede displazi veya ağır displazi veya CIN 2 veya CIN 3 veya Karsinoma in situ ve 14 (%6) hastada malign/skuamöz hücreli karsinom olarak raporlanmıştır. Sonuç: Biyopsi ve smear sonuçları birlikte değerlendirildiğinde 141 (%63) hastada biyopsi ve smear sonuçlarının uyumlu olduğu, 82(%37) hastada ise biyopsi ve smear sonuçlarının farklı olduğu görüldü. Pap smear testinin uygulama kolaylığı ve düşük maliyeti, bu yöntemin yaygın olarak kullanılmasını sağlamıştır. Teknik nedenler ve değerlendirme hatalarına bağlı olarak yanlış negatif sonuçlar görülebilmektedir. Bizim serimizde %63 olguda korelasyon olduğu tesbit edilmiştir. Pap smear ile yanlış negatif oranları %1,1 ile %50 arasında değişiyor olsa da, bu test hala prekanseröz lezyonları tespit etmek için en etkili yöntem olarak kabul edilir.

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The evaluation of Cervical Smear Results Assessed by ThinPrep and Conventional Methods

Semiz¹,

Özbay²,

Yılanlıoglu³

et al. 2019

Zeynep Kamil Tıp Bülteni

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Comparison of cervicovaginal Pap-smear results with clinical parameters

Cited by 3 publications

References 11 publications

Diagnostic Distribution of Cervicovaginal Smear in Bursa and Its Surrounding

Diagnostic Distribution of Cervicovaginal Smear in Bursa and Its Surrounding

Comparison of Cervical Smear and Biopsy Results

The evaluation of Cervical Smear Results Assessed by ThinPrep and Conventional Methods

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