Comparison of caudal ketamine with lidocaine or tramadol administration for postoperative analgesia of hypospadias surgery in children

Gündüz, Murat; Özalevli, M.; Özbek, Hayri; Özcengiz, Dilek

doi:10.1111/j.1460-9592.2005.01650.x

Cited by 26 publications

(12 citation statements)

References 35 publications

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“…In our study, the duration and extent of sensory block provided by spinal bupivacaine were adequate in both groups. The mean operation time was 50 min in our series, a time period comparable to that of hypospadias surgeries reported by others (15,16). We considered complete motor block in the legs as the starting point of anesthesia.…”

Section: Discussionsupporting

confidence: 85%

Efficacy of a low‐dose spinal morphine with bupivacaine for postoperative analgesia in children undergoing hypospadias repair

Apilioğulları

Duman

Gök³

et al. 2009

Pediatric Anesthesia

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Section: Discussionsupporting

confidence: 85%

Efficacy of a low‐dose spinal morphine with bupivacaine for postoperative analgesia in children undergoing hypospadias repair

Apilioğulları

Duman

Gök³

et al. 2009

Pediatric Anesthesia

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“…It has been reported that epidural co-administration of ketamine and lidocaine provided very effective and long duration of post-operative analgesia in children (Gunduz et al 2006). Co-administration of ketamine and lidocaine epidurally increased duration of caudal analgesia in cats and dogs compared with administration of lidocaine or ketamine alone (DeRossi et al 2009;DeRossi et al 2011).…”

Section: Discussionmentioning

confidence: 99%

Caudal epidural analgesia using lidocaine alone or in combination with ketamine in dromedary camels (<i>Camelus dromedarius</i>)

2014

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This study was performed to investigate the analgesic effect of lidocaine and a combination of lidocaine and ketamine following epidural administration in dromedary camels. Ten 12-18-month-old camels were randomly divided into two equal groups. In group L, the animals received 2% lidocaine (0.22 mg/kg) and in group LK the animals received a mixture of 10% ketamine (1 mg/kg) and 2% lidocaine (0.22 mg/kg) administered into the first intercoccygeal (Co1-Co2) epidural space while standing. Onset time and duration of caudal analgesia, sedation level and ataxia were recorded after drug administration. Data were analysed by U Mann-Whitney tests and significance was taken as p < 0.05. The results showed that epidural lidocaine and co-administration of lidocaine and ketamine produced complete analgesia in the tail, anus and perineum. Epidural administration of the lidocaine-ketamine mixture resulted in mild to moderate sedation, whilst the animals that received epidural lidocaine alone were alert and nervous during the study. Ataxia was observed in all test subjects and was slightly more severe in camels that received the lidocaine-ketamine mixture. It was concluded that epidural administration of lidocaine plus ketamine resulted in longer caudal analgesia in standing conscious dromedary camels compared with the effect of administering lidocaine alone.

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“…The contributory effect of the addition of ketamine, an N-methyl-D-aspartate (NMDA) antagonist, was evaluated when the drug is delivered via caudal [6, 8], epidural [18, 19], and spinal [20, 21] routes. In all these studies, addition of ketamine with antagonism to NMDA receptors and an axonal conduction block may also contribute to the analgesic mechanism of regional ketamine to different local anesthetics which provided a success on both block duration and quality.…”

Section: Discussionmentioning

confidence: 99%

“…Numerous studies have been published on the effects of different adjuvants on local anesthetics for axillary brachial plexus block [1–5]. Tramadol and ketamine are the most common adjuvants used with local anesthetics [6, 7]. …”

Section: Introductionmentioning

confidence: 99%

Does the Addition of Tramadol and Ketamine to Ropivacaine Prolong the Axillary Brachial Plexus Block?

Senel

Ukinc

Timurkaynak

2014

BioMed Research International

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Background and Objectives. A prospective, randomized, controlled, double-blind clinical trial to assess the effect of tramadol and ketamine, 50 mg, added to ropivacaine in brachial plexus anesthesia. Methods. Thirty-six ASA physical statuses I and II patients, between 18 and 60 years of age, scheduled for forearm and hand surgery under axillary brachial plexus block, were allocated to 3 groups. Group R received 0.375% ropivacaine in 40 mL, group RT received 0.375% ropivacaine in 40 mL with 50 mg tramadol, and group RK received 0.375% ropivacaine in 40 mL with 50 mg ketamine for axillary brachial plexus block. The onset times and the duration of sensory and motor blocks, duration of analgesia, hemodynamic parameters, and adverse events (nausea, vomiting, and feeling uncomfortable) were recorded. Results. The onset time of sensorial block was the fastest in ropivacaine + tramadol group. Duration of sensorial and motor block was the shortest in the ropivacaine + tramadol group. Duration of analgesia was significantly longer in ropivacaine + tramadol group. Conclusion. We conclude that when added to brachial plexus analgesia at a dose of 50 mg, tramadol extends the onset and duration time of the block and improves the quality of postoperative analgesia without any side effects.

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Comparison of caudal ketamine with lidocaine or tramadol administration for postoperative analgesia of hypospadias surgery in children

Cited by 26 publications

References 35 publications

Efficacy of a low‐dose spinal morphine with bupivacaine for postoperative analgesia in children undergoing hypospadias repair

Efficacy of a low‐dose spinal morphine with bupivacaine for postoperative analgesia in children undergoing hypospadias repair

Caudal epidural analgesia using lidocaine alone or in combination with ketamine in dromedary camels (<i>Camelus dromedarius</i>)

Does the Addition of Tramadol and Ketamine to Ropivacaine Prolong the Axillary Brachial Plexus Block?

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