Comparison of buffered and nonbuffered nasal saline irrigations in treating allergic rhinitis

Chusakul, Supinda; Warathanasin, Sukanya; Suksangpanya, Naphorn; Phannaso, Chuntima; Ruxrungtham, Saran; Snidvongs, Kornkiat; Aeumjaturapat, Songklot

doi:10.1002/lary.23617

Cited by 28 publications

(26 citation statements)

References 20 publications

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“…Chusakul et al (23) investigated three types of isotonic saline solutions according to their alkalinity. The authors inferred that the similarity between the pH of the moderately alkaline solution and the physiological pH of cellular cytoplasm makes its use more soothing to the nasal mucosa cells, thus reducing nasal symptoms.…”

Section: Discussionmentioning

confidence: 99%

“…In short, the protocols analyzed exhibited heterogeneity. Although most of the studies were randomized clinical trials (5,6,12,14,15,23), none obtained the maximum score on the PEDro scale (22), with scores ranging between five and seven points. None of the studies used a control group and four (5,12,14,20) associated nasal irrigation with medication.…”

Section: Methodsmentioning

confidence: 99%

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Isotonic saline nasal irrigation in clinical practice: a literature review

2017

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Introduction: Nasal instillation of saline solution has been used as part of the treatment of patients with upper respiratory tract diseases. Despite its use for a number of years, factors such as the amount of saline solution to be used, degree of salinity, method and frequency of application have yet to be fully explained. Objective: Review the reported outcomes of saline nasal irrigation in adults with allergic rhinitis, acute or chronic sinusitis and after functional endoscopic sinus surgery (FESS), and provide evidence to assist physiotherapists in decision making in clinical practice. Methods: A search was conducted of the Pubmed and Cochrane Library databases between 2007 and 2014. A combination of the following descriptors was used as a search strategy: nasal irrigation, nasal lavage, rhinitis, sinusitis, saline, saline solution. Results: Eight clinical trials were included, analyzed according to participant diagnosis. Conclusion: The evidence found was heterogeneous, but contributed to elucidating uncertainties regarding the use of nasal lavage in the clinical practice of physical therapy, such as the protocols used.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Isotonic saline nasal irrigation in clinical practice: a literature review

2017

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“…Potassium exerts an anti-inflammatory action and, globally, all these ions seem to increase viability in respiratory cells more than isotonic saline [24,25]. Bicarbonate ions reduce mucus viscosity, although the relevance of the addition of pure bicarbonate to the saline solutions is debated [26]. The advantage of the reduced mucous viscosity might be counterbalanced by the increase in the pH of the solution, which might be a negative factor.…”

Section: Mechanisms Of Action Of Nasal Irrigation (Ni)mentioning

confidence: 99%

Nasal Irrigation: An Imprecisely Defined Medical Procedure

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2017

IJERPH

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Nasal irrigation (NI) is an old practice of upper respiratory tract care that likely originated in the Ayurvedic medical tradition. It is used alone or in association with other therapies in several conditions—including chronic rhinosinusitis and allergic rhinitis—and to treat and prevent upper respiratory tract infections, especially in children. However, despite it being largely prescribed in everyday clinical practice, NI is not included or is only briefly mentioned by experts in the guidelines for treatment of upper respiratory tract diseases. In this review, present knowledge about NI and its relevance in clinical practice is discussed to assist physicians in understanding the available evidence and the potential use of this medical intervention. Analysis of the literature showed that NI seems to be effective in the treatment of several acute and chronic sinonasal conditions. However, although in recent years several new studies have been performed, most of the studies that have evaluated NI have relevant methodologic problems. Only multicenter studies enrolling a great number of subjects can solve the problem of the real relevance of NI, and these studies are urgently needed. Methods for performing NI have to be standardized to determine which solutions, devices and durations of treatment are adequate to obtain favorable results. This seems particularly important for children that suffer a great number of sinonasal problems and might benefit significantly from an inexpensive and simple preventive and therapeutic measure such as NI.

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“…Калий оказывает противовоспалительное действие, и в совокупности все вышеперечисленные ионы значительно повышают жизнеспособность респираторных клеток в отличие от изотонического физиологического раствора [15]. Ионы бикарбоната снижают вязкость слизи, хотя актуальность добавления чистого бикарбоната к солевым растворам еще обсуждается [16].…”

Section: Ib Angotoeva¹ Yag Starunova¹ Dp Polyakov² Ak Vinunclassified

A comparative study of different methods of irrigation therapy in adults and children

et al. 2018

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Irrigation therapy is currently an integral part of the prevention and treatment of various ENT diseases. In and amongst all the variety of drugs of irrigation therapy, intranasal sprays are the most widely available. The article presents a comparative study of the intranasal spray characteristics. The advantages of using Marimer spray include minimal discomfort, jet sensation; the spray gets into the nasopharynx, but does not cause the Eustachian tube dysfunction.

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Comparison of buffered and nonbuffered nasal saline irrigations in treating allergic rhinitis

Abstract: Buffered isotonic saline with some degree of alkalinity may improve nasal symptoms. Isotonic saline irrigations, regardless of alkalinity, may not improve mucociliary function and nasal patency. Buffered isotonic saline with mild alkalinity is the most preferred.

Cited by 28 publications

References 20 publications

Isotonic saline nasal irrigation in clinical practice: a literature review

Isotonic saline nasal irrigation in clinical practice: a literature review

Nasal Irrigation: An Imprecisely Defined Medical Procedure

A comparative study of different methods of irrigation therapy in adults and children

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