Comparison of Bone Graft Healing Between Autogenous Bone, Blood Clot and Anorganic Bovine Bone Matrix: Radiographic and Histological Analyses

Abstract

SUMMARY:Surgical procedures involving the rehabilitation of the maxillofacial region frequently require use of bone grafts. Bone graft follow-up is generally done through clinical analysis and especially through image tests, although few studies specifically correlate both. The object of this research was to establish a relation between radiographic exams and the bone repair process stage in created defect with autogenous bone, blood clot and anorganic bovine bone matrix. Three 8 mm diameter defects were performed in the parietal bone of 6 male adult beagle dogs, choosing the selected graft for each defects; 3 and 6 week period were used for radiographic and histological analyses. The result show that autogenous bone and blood clot were similar between histological and radiograph analyses; for heterogeneous bone was present areas described how bone in radiograph that were residual particles in histological exam. We concluded that radiographic tests could be used as a parameter for reconstruction follow-up only when autogenous bone graft is used.

Variation in the Repair of a Rib Graft used for Mandibular Reconstruction after 20 years

“…Until the end of the 1970s the bone graft was stabilized and fixed with wires, combined with long periods of intermaxillary fixation. Today, the free bone graft is frequently transplanted from the anterior iliac crest in block form and stabilized at the reconstruction site with plates and titanium screws (Bak et al, 2010;Olate et al, 2013).…”

The Effects of Regenerative Materials on Biomarkers, Clinical and Radiological Features of Healing Defects Treated by Guided Bone Regeneration

“…Events like cell migration, proliferation, chemotaxis, differentiation and synthesis of extracellular proteins taking place during bone healing process are closely related to the rate of healing which varies with the type of regenerative materials as well [20]. In fact, prominent inflammatory cells have been reported beyond two months in sites treated by regenerative materials, while less inflammation is seen in auto grafts [20].…”

“…In fact, prominent inflammatory cells have been reported beyond two months in sites treated by regenerative materials, while less inflammation is seen in auto grafts [20]. Due to difference in cellular and mineral components of regenerated bones, it is hypothesized that all of these events are modulated when defects are treated with different BRMs.…”

A comparative study of platelet rich fibrin and bone graft in intrabony defect treatment: A systematic review

“…PRF has been demonstrated to release polypeptide growth factors such as transforming growth factor β1, platelet-derived growth factor, vascular endothelial growth factor and matrix glycoproteins (such as thrombospondin-1) gradually over at least 1 week. [4][5][6] The aim of the present review is to systematically evaluate the effect of treatment using platelet rich fibrin and/or bone graft in intrabony defect cases by obseving clinical or radiological outcomes.…”