Comparison of Bleeding Time and Clotting Time in Different Blood Groups

Abstract

Problem statement:Researchers have demonstrated that epistaxis is more often encountered in patients having blood group O probably due to lower expression of von Willebrand factor. We had taken up this study to find out if there is any definite relationship between the blood groups with the bleeding time and clotting time in our population. Approach: This retrospective study was conducted in the department of physiology in our institution. The available detail reports of 740 students passing through 1st year of MBBS over the years from 1999-2007 were analyzed in respect of age, sex, blood groups, bleeding time and clotting time. The blood grouping was done with the standard antisera and bleeding time and clotting time were estimated by Duke method and capillary tube method respectively. Finally bleeding time and clotting time of different blood groups were compared and statistical analysis was done. Results: In present study population O group was found in more number of cases (37.8%) than A, B and AB. Clotting time was found to be prolonged more than 6 min in maximum number of cases in B group (12.7 cases) followed by A group (8) and O group (5.8) and AB group (4.3%). Similarly bleeding time was more than 4 min in AB group in 21.8 followed by 13.9 in group B, 10.5 in group A and 9.6% in group O. Conclusion: In present study population interestingly clotting time was more in blood group AB and bleeding time in blood group B than other blood groups which was statistically significant. Further study needed to correlate the association of this finding in cases of epistaxis and hemoptysis in our population.

Relationship Between Bleeding Time And Clotting Time Among Gender Difference And Varying Blood Groups In UG Medical Student

“…This means that the clotting time and the bleeding time will be elevated among the O group individuals compared to the other groups. But, as per the study done by Mahapatra et al (15), clotting time was prolonged in the group Bindividuals and bleeding time was prolonged in the AB group compared to other groups. Out study also proved the same findings where the bleeding time was comparatively increased among the B group and the clotting time was increased in the individuals among AB group.…”

Bleeding Time and Clotting Time in Different Blood Groups- A Cross Sectional Study

“…Evaluation of blood groups, bleeding time and clotting time are the most important and initial haematological parameters. In a study by B Mahapatra et al (4) O group was found in more number of students (37.8%) than A (21.9%), B (34%) and AB (6.3%). In another study by Roy B et al, (1) O blood group was also the more prevalent group (35.2%) than A (30.5%), B (28.9%) and AB (5.5%).…”

“…This was in contrast to the study performed by Mahapatra B et al where BT was more in B blood group. (4) In another study by Baishya R et al, BT was most prolonged in O group. (5) Aleem A et al found Bleeding time to be greater than others in AB blood group in females and 'O' blood group in males but the values were not significantly different.…”

“…This was in contrast to the study of Mahapatra B et al where CT was found to be more prolonged in AB group. (4) Baishya R et al found prolonged CT in O group. (5) Aleem A et al found significantly higher Clotting time in O blood group in females, and in B blood group and males.…”

“…(9) However, in another study done by Mahapatra B et al, there was no difference in the bleeding time and clotting time among the males and females. (4) A study with a bigger sample size may give a better picture.…”