Comparison of Balloon Angioplasty and Laser Thermal Angioplasty in the Treatment of Femoropopliteal Atherosclerotic Disease: Initial Results of a Prospective Randomized Trial

“…Laser atherectomy, also known as laser-assisted balloon angioplasty, was initially introduced in the 1980s for the treatment of peripheral arterial disease. 1 Neodymium:YAG lasers successfully delivered sufficient energy to debulk and successfully cross long occlusions and stenosis. 2 Unfortunately, a great deal of thermal energy was produced, leading to vessel wall damage.…”

mentioning

confidence: 99%

Mid-term results with laser atherectomy in the treatment of infrainguinal occlusive disease

Stoner

deFreitas

Phade

et al. 2007

Journal of Vascular Surgery

View full text Add to dashboard Cite

show abstract

“…Forty RCTs were accepted into the narrative review, published in 61 references. Study characteristics are shown in Table S1 (supporting information). Most of the trials recruited participants who had angioplasty of the superficial femoral and/or popliteal artery.…”

Section: Resultsmentioning

confidence: 99%

Systematic review and meta-analysis of additional technologies to enhance angioplasty for infrainguinal peripheral arterial occlusive disease

Simpson

Michaels

Thomas

et al. 2013

British Journal of Surgery

View full text Add to dashboard Cite

Background: There are several additional techniques designed to enhance conventional percutaneous transluminal balloon angioplasty (PTA). This systematic review assessed current evidence on the clinical effectiveness of additional techniques for infrainguinal peripheral arterial occlusive disease (PAD).Methods: Relevant electronic databases, including MEDLINE, were searched in May 2011. The population comprised participants with symptomatic PAD undergoing endovascular treatment for disease distal to the inguinal ligament. Interventions were additional techniques compared with conventional PTA. Main outcome measures were restenosis and need for reintervention. Randomized clinical trials (RCTs) of clinical effectiveness were assessed for quality and data were extracted. Where appropriate, meta-analysis was undertaken to produce risk ratios (RRs).Results: Forty RCTs were selected. Meta-analysis showed a significant benefit in reducing restenosis rates at 6 months for self-expanding stents (RR 0·49) and drug-coated balloons (RR 0·40), and at 12 months for endovascular brachytherapy (RR 0·63). There was also evidence that use of a stent-graft significantly reduced restenosis compared with PTA, as did drug-eluting stents compared with baremetal stents. Meta-analysis showed that use of drug-coated balloons was associated with significantly lower reintervention rates than PTA alone at 6 months (RR 0·24) and 24 months (RR 0·27) of follow-up. There was also evidence of significantly lower reintervention rates for self-expanding stents at 6 months. Other techniques did not show significant treatment effects for restenosis or reintervention. Conclusion:The conclusions of this review should be tempered by small sample sizes, lack of clinical outcome measures and differing outcome definitions, making direct comparison across trials difficult. However, self-expanding stents, drug-eluting stents and drug-coated balloons appeared to be the most promising technologies worthy of future study.

show abstract

Comparison of Balloon Angioplasty and Laser Thermal Angioplasty in the Treatment of Femoropopliteal Atherosclerotic Disease: Initial Results of a Prospective Randomized Trial

Cited by 15 publications

References 16 publications

Enhancements to angioplasty for peripheral arterial occlusive disease: systematic review, cost-effectiveness assessment and expected value of information analysis

Enhancements to angioplasty for peripheral arterial occlusive disease: systematic review, cost-effectiveness assessment and expected value of information analysis

Mid-term results with laser atherectomy in the treatment of infrainguinal occlusive disease

Systematic review and meta-analysis of additional technologies to enhance angioplasty for infrainguinal peripheral arterial occlusive disease

Contact Info

Product

Resources

About