Comparison of autogenous cancellous bone grafting and extra-corporeal shock wave therapy on osteotomy healing in the tibial tuberosity advancement procedure in dogs

Abstract

There were no significant differences in the osteotomy gap density at eight weeks after surgery regardless of the treatment modality used. The combination of autogenous cancellous bone graft and extracorporeal shock wave therapy may lead to increased radiographic density of the osteotomy gap in the first four weeks after surgery. Densitometry using an aluminium step wedge is a feasible method for comparison of bone density after TTA in dogs.

Extracorporeal Shock Wave Therapy in Acute Injury Care: A Systematic Review

“…30,31 Detected effects include the upregulation of vascular endothelial growth factor (VEGF), VEGF receptor protein, placental growth factor (PGF), PGF receptor protein, transforming growth factor β 1 , basic fibroblast growth factor, insulinlike growth factor, and bone morphogenetic protein, accompanied by an increased presence of mitotic precursor cells, the formation of new blood vessels, and accelerated healing. Observed increased union rates and enhanced recovery of mechanical properties in surgically and accidentally induced bone fractures in rabbits and dogs [32][33][34] and higher tensile load of injured patellar tendons in rabbits 35 are in close relation to described biological ESWT effects.…”

“…Similar to skin wounds, broad experience from nonunion treatment in the chronic range, 50,51 just as from acute fracture treatment in animal studies (eg, the works by Wang et al 25 and Oktaş et al 52 ) and clinical veterinary medicine, 33,34 suggests that ESWT should have a positive perspective if applied to fresh fractures of human bone (Table 2). However, regardless of these indications, evidence supporting that the animal-based assessment might be transferable to fresh fracture healing in humans is still limited.…”