Comparison of attenuation, dual-energy-window, and model-based scatter correction of low-count SPECT to 82Rb PET/CT quantified myocardial perfusion scores

Wells, R. Glenn; Soueidan, Karen; Timmins, Rachel; Ruddy, Terrence D.

doi:10.1007/s12350-013-9738-7

Cited by 7 publications

(1 citation statement)

References 29 publications

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“…However, its power to diagnose and evaluate the extent of disease in patients who are suspected for coronary artery disease (CAD) or in those with already established CAD is mainly hampered by its somewhat low specificity, limited spatial resolution, and difficulties for absolute quantification. To overcome these limitations of SPECT-assessed myocardial perfusion, attempts have been made with a varying degree of success, including the use of attenuation correction and scatter correction, new crystal and collimator systems, advanced processing software [1,2]. However, the majority of these (technical) SPECT related limitations can be overcome with positron emission computed tomography (PET).…”

Section: Introductionmentioning

confidence: 99%

Left ventricular function in response to dipyridamole stress: head-to-head comparison between 82Rubidium PET and 99mTc-sestamibi SPECT ECG-gated myocardial perfusion imaging

Giorgi

Meneghetti

Soares

et al. 2016

Eur J Nucl Med Mol Imaging

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Rb summed rest (SRS), stress (SSS) and difference (SDS) scores, and LV end-diastolic (EDV) and end-systolic (ESV) volumes and left ventricular ejection fraction (LVEF) were compared. Results Bland-Altman analysis showed that with increasing ESVand EDV the difference between the two perfusion tracers increased both at rest and post-stress. The mean difference in EDV and ESV between the two perfusion tracers at rest could both be independently explained by the 82 Rb SDS and the sestamibi SRS. The combined models explained approximately 30% of the variation in these volumes between the two perfusion tracers (R 2 = 0.261, p = 0.005; R 2 = 0.296, p < 0.001, for EDVand ESV respectively). However, the mean difference in LVEF between sestamibi and

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Section: Introductionmentioning

confidence: 99%

Left ventricular function in response to dipyridamole stress: head-to-head comparison between 82Rubidium PET and 99mTc-sestamibi SPECT ECG-gated myocardial perfusion imaging

Giorgi

Meneghetti

Soares

et al. 2016

Eur J Nucl Med Mol Imaging

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Comparative analysis of iterative reconstruction algorithms with resolution recovery for cardiac SPECT studies. A multi-center phantom study

Zoccarato

Scabbio

Ponti

et al. 2014

Journal of Nuclear Cardiology

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This is the first study comparing the relative performance of different, commercially available, IRR software, over a wide range of count statistics; the additional effect of scatter and attenuation corrections, alone or in combination, was also evaluated. Our results confirm that IRR algorithms produce substantial benefits with respect to conventional FBP or OSEM reconstruction methods, as assessed through different figures of merit, in particular when SC and/or SCAC are also included.

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Scatter correction improves concordance in SPECT MPI with a dedicated cardiac SPECT solid-state camera

Pourmoghaddas

Vanderwerf

Ruddy

et al. 2015

Journal of Nuclear Cardiology

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Comparison of attenuation, dual-energy-window, and model-based scatter correction of low-count SPECT to 82Rb PET/CT quantified myocardial perfusion scores

Abstract: AC significantly improves the accuracy of low-count myocardial perfusion SPECT half-time imaging for the detection of disease compared to NC. Compared to PET, there was no significant difference among AC, AC-DEW, and AC-ESSE.

Cited by 7 publications

References 29 publications

Left ventricular function in response to dipyridamole stress: head-to-head comparison between 82Rubidium PET and 99mTc-sestamibi SPECT ECG-gated myocardial perfusion imaging

Left ventricular function in response to dipyridamole stress: head-to-head comparison between 82Rubidium PET and 99mTc-sestamibi SPECT ECG-gated myocardial perfusion imaging

Comparative analysis of iterative reconstruction algorithms with resolution recovery for cardiac SPECT studies. A multi-center phantom study

Scatter correction improves concordance in SPECT MPI with a dedicated cardiac SPECT solid-state camera

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