2008
DOI: 10.1192/bjp.bp.107.042630
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Comparison of antipsychotic medication effects on reducing violence in people with schizophrenia

Abstract: Newer antipsychotics did not reduce violence more than perphenazine. Effective antipsychotics are needed, but may not reduce violence unrelated to acute psychopathology.

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Cited by 170 publications
(139 citation statements)
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References 39 publications
(55 reference statements)
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“…In relation to the management of persistent violence, however, the contribution of other atypical antipsychotics remains uncertain [52]. Future research also is urgently needed to clarify whether antipsychotics reduce violence only in those individuals whose aggressive behaviour is driven by their psychotic symptomatology, or whether they lead to neurobiological changes that reduce violence independently of decreased psychotic symptoms [50]. Additionally, we found evidence that nonadherence with medication increased violence risk.…”
Section: Discussionmentioning
confidence: 86%
“…In relation to the management of persistent violence, however, the contribution of other atypical antipsychotics remains uncertain [52]. Future research also is urgently needed to clarify whether antipsychotics reduce violence only in those individuals whose aggressive behaviour is driven by their psychotic symptomatology, or whether they lead to neurobiological changes that reduce violence independently of decreased psychotic symptoms [50]. Additionally, we found evidence that nonadherence with medication increased violence risk.…”
Section: Discussionmentioning
confidence: 86%
“…23,24 Conversely, in agreement with the general view, scientific evidence suggests that individuals who undergo adequate treatment are less likely to commit violent acts. 25 Among the variables evaluated, labeling the vignette as "mental illness" and attributing "biological causes" showed statistical association with perceived dangerousness.…”
Section: Perceived Dangerousnessmentioning
confidence: 99%
“…Fung et al (2009) It is crucial to understand aggressive behavior in children and adolescents to know the different forms of aggressive behavior in order to demonstrate effective approaches for prevention and intervention, and to provide specific approaches to different forms of aggression (Raine et al, 2006). Indeed, clinical research indicates that different intervention programs are effective with different forms of aggression (Antonius et al, 2013;Swanson et al, 2008;. Anger management and social cognitive reconstruction especially with regard to self-attribution biases can be used in studies with reactive aggression.…”
Section: Introductionmentioning
confidence: 99%