Comparison of Antimicrobial Efficacy of Diode Laser, Triphala, and Sodium Hypochlorite in Primary Root Canals: A Randomized Controlled Trial

Thomas, Seby; Asokan, Sharath; John, Baby; Priya, P R Geetha; Kumar, Senthil

doi:10.5005/jp-journals-10005-1399

Cited by 13 publications

(9 citation statements)

References 15 publications

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“… 40 , 41 A study using human primary teeth ex vivo revealed that Triphala suspended in 10% DMSO (1:3) exhibited significant antibacterial activity compared with control as well as higher antibacterial activity compared with 3% NaOCl. 42 In vitro studies using Triphala ethanol extract have reported similar antimicrobial effects against E. faecalis compared with 2.5% NaOCl. 43 Thus, Triphala may represent a potential therapy to eliminate E. faecalis as more side-effects and larger risk are associated with NaOCl solution treatment.…”

Section: Therapeutic Uses and Studiesmentioning

confidence: 97%

Therapeutic Uses ofTriphalain Ayurvedic Medicine

Peterson

Denniston

Chopra

2017

The Journal of Alternative and Complementary Medicine

247

156

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Aim: The aim of this article is to review the current literature on the therapeutic uses and efficacy of Triphala. Herbal remedies are among the most ancient medicines used in traditional systems of healthcare such as Ayurveda. Triphala, a well-recognized and highly efficacious polyherbal Ayurvedic medicine consisting of fruits of the plant species Emblica officinalis (Amalaki), Terminalia bellerica (Bibhitaki), and Terminalia chebula (Haritaki), is a cornerstone of gastrointestinal and rejuvenative treatment.Methods: A search of the PubMed database was conducted.Results: In addition, numerous additional therapeutic uses described both in the Ayurvedic medical literature and anecdotally are being validated scientifically. In addition to laxative action, Triphala research has found the formula to be potentially effective for several clinical uses such as appetite stimulation, reduction of hyperacidity, antioxidant, anti-inflammatory, immunomodulating, antibacterial, antimutagenic, adaptogenic, hypoglycemic, antineoplastic, chemoprotective, and radioprotective effects, and prevention of dental caries. Polyphenols in Triphala modulate the human gut microbiome and thereby promote the growth of beneficial Bifidobacteria and Lactobacillus while inhibiting the growth of undesirable gut microbes. The bioactivity of Triphala is elicited by gut microbiota to generate a variety of anti-inflammatory compounds.Conclusions: This review summarizes recent data on pharmacological properties and clinical effects of Triphala while highlighting areas in need of additional investigation and clinical development.

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Section: Therapeutic Uses and Studiesmentioning

confidence: 97%

Therapeutic Uses ofTriphalain Ayurvedic Medicine

Peterson

Denniston

Chopra

2017

The Journal of Alternative and Complementary Medicine

247

156

View full text Add to dashboard Cite

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“…The diode laser has a thermal photo disruptive action in dentin, which increases the root canal system's bactericidal effect. 24 Passive ultrasonic activation of the root canal irrigant is a predominant step in the endodontic treatment procedure. One of the main reasons that the activation of the irrigant is an essential step in the endodontic procedure is to create an acoustic streaming effect that enhances the wall shear stress and also it has a great role in distrust-ing the biofilm within the canal .Also, during irrigation ultrasonic creates a faster flow volume of the irrigant into the root canal, resulting in better debris and smear layer removal, less apical packing, and improved chemical product reaching to accessory canals and isthmuses.…”

Section: Discussionmentioning

confidence: 99%

Antibacterial effectiveness of different final irrigation activation techniques.

Mustafa,

Selivany,

Ali

2023

EDJ

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Background and objective: To evaluate and compare the antibacterial effectiveness of ultrasonic, diode laser, XP endo finisher and finisher gentle file brush against Enterococcus faecalis in root canal dentin. Methods: Fifty-five single-rooted extracted mandibular premolars were decoronated to have a length of 12 mm, instrumented biomechanically with protaper Next up to size X3. After sterilization, five roots were selected as negative controls and the remaining teeth were inoculated with E. faecalis and incubated for 48 hr and at 37 ºC. The roots were then randomly divided into five groups (n=10), GI: Control group, GII: 5.25% NaOCl irrigation was activated by the ultrasonic system , GIII: By 980-nm diode laser , GIV: By Xp-endo finisher and GV : Activated by Finisher gentle file-brush. The antimicrobial efficacy was tested by collecting transfer fluid saline from the canals and counting the colony forming units (CFUs) of viable E. faecalis on agar plates. The statistical calculations were performed in JMP pro 14.3.0. using Analysis of Variance (ANOVA) followed by a Tukey test to define the differences between the tested groups. Result: The mean bacterial CFU were 10.6 X 10^7 for Finisher gentle file brush, 35.6×10^7 for Diode laser, 39.6×10^7 for ultrasonic and 42.3×10^7 for XP Endo Finisher. Finisher gentle file brush showed a significant reduction in the colony count compared to the other groups. Conclusion: None of the irrigation activation techniques removed the bacteria completely from the canal. The four tested irrigation activation techniques were shown to be effective in the disinfection of the E. faecalis-contaminated root canals. Finisher gentle file brush was the most effective against E. faecalis, while XP endo finisher was the least effective against E. faecalis. treatment against E. faecalis in the root canal. Keywords: Utrasonic, Diode laser, XP endo finisher, irrigation activation techniques

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“…The dried powders A. arabica (bark), T. Chebula (fruits), T. bellerica (fruits) and E. officinalis (fruits) plants have been used in traditional tooth powder formulation in India for more than 100 years (unpublished). Already many reports are available for the validation of numerous of potential benefits of these four plant material including anti-cariogenic properties [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] and these plant materials possess abundance of bioactive compound like quercetin, luteolin, saponins, anthraquinones, amino acids, fatty acids, various carbohydrates and polyphenols such as chebulinic acid which can exhibit the antimicrobial activities [34] , [35] . The above four plant materials used in this study having the potential to protect users against oral diseases, but this potential and the possible mechanism has not been investigated.…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial effect of herbal extract of Acacia arabica with triphala on the biofilm forming cariogenic microorganisms

Ramalingam

2020

Journal of Ayurveda and Integrative Medicine

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Background Dental caries is a biofilm-related infectious disease with a multifactorial etiology, over five billion inhabitants have affected worldwide due to this disease. Objective Antimicrobial efficacy of a mixed herbal powder extract (MHPE) against cariogenic microorganisms was investigated. Materials and methods MIC, MBC, kinetics of killing, biofilm disruption and anticaries effect of MHPE were determined. For biofilm disruption, biofilms of Streptococcus mutans, Lactobacillus casei, Actinomyces viscosus and Candida albicans were treated with MHPE for 30 min and attached cells were quantified after staining. For live/dead staining biofilm assay, S. mutans biofilm treated with MHPE for 1min, 5min and 1 h was examined with confocal laser scanning system after live/dead staining. Efficacy was experimented by structural quality using Scanning Electron Microscope (SEM). Anticaries effect was determined by formation of caries-like lesion in continuous flow biofilm model. Results MHPE exhibited inhibition zones ranging from 12.5 to 24.0 mm. The highest inhibition zone was recorded at concentration of 50 μg/ml. MIC for S. mutans was between 12.23 and 36.7 μg/ml, while the MBC values ranged from 36.7 to 110.65 μg/ml. Inhibitory concentration of MHPE was three fold higher than CHLX. Significant reduction of cell count (49–95%) was observed with increasing time and higher concentration. Percentage biofilm reduction compare with negative control was 96.9% ( A. viscosus) , 94% ( C. albicans) , 99.8% ( L. casei) and 91.7% ( S. mutans) . For MHPE-treated biofilm, live/dead staining demonstrated significant (p < 0.05) higher in deceased red fluorescence areas in all kinetics points from 53.6% (1min) to 85% (1h). SEM confirmed the damage in the outer layers of S. mutans. MHPE has components with effective antibacterial activity against caries-inducing microorganisms. Conclusion The anti-adherence and anti-biofilm effect as well as the faster killing activity suggests that MHPE formula has effective antibacterial activity and could be a useful source of anti-cariogenic agents in near future.

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Comparison of Antimicrobial Efficacy of Diode Laser, Triphala, and Sodium Hypochlorite in Primary Root Canals: A Randomized Controlled Trial

Cited by 13 publications

References 15 publications

Therapeutic Uses ofTriphalain Ayurvedic Medicine

Therapeutic Uses ofTriphalain Ayurvedic Medicine

Antibacterial effectiveness of different final irrigation activation techniques.

Antimicrobial effect of herbal extract of Acacia arabica with triphala on the biofilm forming cariogenic microorganisms

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