Comparison of Analytic Algorithms for Detecting Glaucomatous Visual Field Loss

Katz, Joanne; Sommer, Alfred; Gaasterland, Douglas E.; Anderson, Douglas R.

doi:10.1001/archopht.1991.01080120068028

Cited by 175 publications

(91 citation statements)

References 22 publications

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“…By comparing number of eyes with clusters of significantly depressed test point locations, defined as three or more adjacent points, with at least one point depressed at the p<2% level, requiring that cluster points be located in the same upper or lower hemifield. This criterion is similar to the one suggested by Katz and co-workers 1991 15 .…”

Section: By Paired Comparisons Of Number Of Significantly Depressed Psupporting

confidence: 87%

Diagnostic Sensitivity of Fast Blue–Yellow and Standard Automated Perimetry in Early Glaucoma

Bengtsson

Heijl

2006

Ophthalmology

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Purpose: To compare the ability of fast Swedish interactive threshold algorithm (SITA) shortwavelength-automated-perimetry (SWAP), lengthier Full Threshold SWAP, and Standard Automated Perimetry (SAP) to detect early glaucomatous visual field loss.Design: Cross-sectional, prospective study of perimetric diagnostic sensitivity as defined by reference limits determined in the same healthy subjects for all three test programs. Conclusion: SITA SWAP identified at least as much glaucomatous visual field loss as the older Full Threshold SWAP although test time was considerably reduced. Conventional SAP using SITA Fast was not significantly less sensitive than either of the two SWAP programs.

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Section: By Paired Comparisons Of Number Of Significantly Depressed Psupporting

confidence: 87%

Diagnostic Sensitivity of Fast Blue–Yellow and Standard Automated Perimetry in Early Glaucoma

Bengtsson

Heijl

2006

Ophthalmology

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“…The VF was considered to be abnormal if it was classified as outside normal limits by the GHT or if three or more contiguous test locations in the pattern deviation plot were depressed significantly at the Po5% level with at least one at the Po1% level on the same side of the horizontal meridian. 22 VF abnormalities were classified as mild (mean deviation (MD) 4 À 6 decibels (dB)), moderate ( À 12 dB o MD r À 6 dB), or severe (MD r À 12 dB). If both eyes were normal or had glaucoma, one eye was selected randomly by the investigator, who was masked to the OCT results at the time the selection was made with a random number generator statistical table.…”

Section: Participants and Examinationsmentioning

confidence: 99%

Correlation of localized glaucomatous visual field defects and spectral domain optical coherence tomography retinal nerve fiber layer thinning using a modified structure–function map for OCT

Boer

Chen

et al. 2015

Eye

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Purpose To study the correlation between glaucomatous visual field (VF) defects assessed by standard automated perimetry (SAP) and peripapillary retinal nerve fiber layer (RNFL) thinning measured by spectral domain optical coherence tomography (OCT) using a modified OCT-based peripapillary RNFL structure-function map. Patients and methods Perimetric glaucoma patients and age-matched normal control subjects were recruited from a university hospital clinic. All eyes underwent testing with the Spectralis spectral domain OCT and SAP on the same day. An OCT-based correspondence map, which correlated VF areas with peripapillary RNFL sectors was created to evaluate the relationship between glaucomatous RNFL thinning and VF loss in six nerve fiber layer bundle areas. Correlations of RNFL thinning with corresponding VF defects were examined using Spearman rankorder correlations. To demonstrate the association between localized VF defects and RNFL thickness, the theoretical curves were made according to an established log-linear model. The measured RNFL thickness values and VF defects were presented in the same scatterplot for each sector. Results Fifty-six glaucoma patients and 85 normal subjects were included in the study.Significant association between localized VF loss and RNFL thinning was found in corresponding areas. Data from the current study fit well with established log-linear models, which compare RNFL thickness values with VF defects. Conclusion Analysis of RNFL thinning in eyes with localized glaucomatous VF defects showed good structure-function correlation in a new OCT-based structure-function correspondence map.

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“…Three adjacent non-edge points Po0.05 in the pattern deviation probability plot of which at least one point Po0.01 and all points on the same side of the horizontal meridian (LTG-P criterion). 6 For conversion, two consecutive, reliable 5 tests had to be classified as abnormal 7,8 (according to any of the criteria as listed above), and any reliable test performed after these two tests had to be abnormal as well. Defects had to be in the same hemifield and at least partially overlapping.…”

Section: Perimetrymentioning

confidence: 99%

The groningen longitudinal glaucoma study III. The predictive value of frequency-doubling perimetry and GDx nerve fibre analyser test results for the development of glaucomatous visual field loss

Heeg

Jansonius

2008

Eye

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Purpose To investigate whether frequencydoubling perimetry (FDT) and nerve fibre analyser (GDx) test results are able to predict glaucomatous visual field loss in glaucoma suspect patients. Methods A large cohort of glaucoma suspect patients (patients with ocular hypertension or a positive family history of glaucoma without visual field abnormalities at baseline) was followed prospectively for 4 years with SAP (HFA 30-2 SITA fast), FDT (C-20 full threshold), and GDx (version 2.010) in a clinical setting. After the follow-up period, baseline FDT and GDx test results of converters (glaucoma suspect patients who had converted to a reproducible abnormal SAP test result during follow-up) were compared to that of non-converters (suspects with normal SAP test results at the end of the follow-up) by calculating relative risks. Cutoff point for FDT was 41 depressed test point Po0.01 in the total deviation probability plot; cutoff point for GDx was the number 429. Results Of 174 glaucoma suspect patients, 26 had developed reproducible glaucomatous visual field loss (conversion rate: 3.7% per year). Relative risk was 1.8 (95% confidence interval: 0.9-3.7; P ¼ 0.10) for FDT and 2.7 (95% confidence interval: 1.2-6.3; P ¼ 0.01) for GDx. Positive predictive value was 0.22 for both FDT and GDx; negative predictive value was 0.88 for FDT and 0.92 for GDx. Conclusions In a clinical setting, especially GDx may be helpful for identifying glaucoma suspect patients at risk of developing glaucomatous visual field loss as assessed by SAP.

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Comparison of Analytic Algorithms for Detecting Glaucomatous Visual Field Loss

Cited by 175 publications

References 22 publications

Diagnostic Sensitivity of Fast Blue–Yellow and Standard Automated Perimetry in Early Glaucoma

Diagnostic Sensitivity of Fast Blue–Yellow and Standard Automated Perimetry in Early Glaucoma

Correlation of localized glaucomatous visual field defects and spectral domain optical coherence tomography retinal nerve fiber layer thinning using a modified structure–function map for OCT

The groningen longitudinal glaucoma study III. The predictive value of frequency-doubling perimetry and GDx nerve fibre analyser test results for the development of glaucomatous visual field loss

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