Comparison of alfentanil, fentanyl and enflurane as supplements to general anaesthesia for outpatient gynaecologic surgery

Abstract

We compared two narcotic/N2O anaesthetic techniques and an inhalational anaesthesia/N2O technique for outpatient surgery in 59 women undergoing short gynaecological procedures. All patients received droperidol 0.625 mg IV, thiopentone and 70 per cent N2O in O2 plus either alfentanil (15 micrograms.kg-1), fentanyl (1.5 microgram.kg-1) or enflurane. The narcotics were given in a double-blind fashion and all anaesthetic techniques were assigned randomly. Cardiorespiratory parameters remained stable in all groups, with few clinically important changes occurring. Recovery was significantly faster in the group receiving alfentanil, with the time to respond to verbal commands and the time to establish alertness significantly faster than with either fentanyl or enflurane. All techniques provided satisfactory anaesthesia; however, the patients receiving alfentanil had significantly more adverse events than those receiving fentanyl.

Which anaesthetic agents are cost-effective in day surgery? Literature review, national survey of practice and randomised controlled trial

“…Three groups in which alfentanil, fentanyl and enflurane were used for maintenance anaesthesia were examined in a second study. 80 Alfentanil was better than fentanyl, and both these agents were better than enflurane with respect to early, intermediate or late recovery. When remifentanil was compared to alfentanil 59 no difference was found with respect to early, intermediate or late recovery, although the patients in the remifentanil group performed better on psychomotor testing.…”

Acupressure wristbands do not prevent postoperative nausea and vomiting after urological endoscopic surgery

“…1 The incidence of PONV may be as high as 60-70% which is influenced by various factors in the perioperative period including patient characteristics. [2][3][4][5][6] The medications used to alleviate PONV may be associated with side effects varying from lethargy, restlessness, tachycardia and extrapyramidal symptoms.…”