Comparison of air kerma rate between the S7500 and S7600 xoft axxent sources

Abstract

PURPOSE:The purpose of this work was to evaluate differences in air-kerma rate of the older, S7500 water-cooled Xoft Axxent source and newer, S7600 Galden-cooled source. METHODS AND MATERIALS:The Attix Free Air Chamber (FAC) at the UWMRRC was used to measure the air-kerma rate at 50 cm for six S7600 Xoft Axxent sources. The average measured air-kerma of the S7600 sources was compared with the measured average air-kerma rate from five S7500 sources. The air-kerma rates of the S7500 sources were measured in a Standard Imaging HDR 1000 + well chamber. The FAC measurements were used to determine a well chamber calibration coefficient for the S7600 source. The S7500 calibration coefficients were incorrectly applied to the S7600 sources to indicate the magnitude of error that can occur if the incorrect calibration coefficient is used. RESULTS: A 10.3% difference was observed between the average air-kerma rates of the two sources although a 17% difference was observed between their calibration coefficients. The application of the S7500 calibration coefficient to the S7600 sources resulted in measured air-kerma rates that were 20% greater than the true value. CONCLUSIONS: This work indicates the need for a new air-kerma rate standard for the S7600 sources, and the results presented in this work are indicative of values that would be obtained at National Institute of Standards and Technology.

Biological Characterization of the Effects of Filtration on the Xoft Axxent® Electronic Brachytherapy Source for Cervical Cancer Applications

“…This coolant has a density of 1.72 g/cc and a lower heat capacity compared to water ( 5 ). The changes made to these sources have been shown to affect the source output and thus, it is important that each source model have its own characterization performed ( 6 ). The Axxent ® sources are used to deliver a localized dose of radiation to a patient, similar to a traditional, radioactive brachytherapy source, and are approved for a variety of applications, including the treatment of skin cancers, gynecological disease, and breast cavities ( 3, 7–10 ).…”