2021
DOI: 10.1186/s42826-021-00088-y
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Comparison of age‐dependent alterations in thioredoxin 2 and thioredoxin reductase 2 expressions in hippocampi between mice and rats

Abstract: Background Aging is one of major causes triggering neurophysiological changes in many brain substructures, including the hippocampus, which has a major role in learning and memory. Thioredoxin (Trx) is a class of small redox proteins. Among the Trx family, Trx2 plays an important role in the regulation of mitochondrial membrane potential and is controlled by TrxR2. Hitherto, age-dependent alterations in Trx2 and TrxR2 in aged hippocampi have been poorly investigated. Therefore, the aim of this … Show more

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“…As described previously [ 68 ], the immunoblots of TRPV1 and TRPV4 were analyzed using Scion Image software from Scion Crop (Frederick, MD, USA). The bands were scanned, and densitometric analysis was performed.…”
Section: Methodsmentioning
confidence: 99%
“…As described previously [ 68 ], the immunoblots of TRPV1 and TRPV4 were analyzed using Scion Image software from Scion Crop (Frederick, MD, USA). The bands were scanned, and densitometric analysis was performed.…”
Section: Methodsmentioning
confidence: 99%