2003
DOI: 10.1067/mhj.2003.90
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Comparison of a silicon carbide-coated stent versus a noncoated stent in human beings: The Tenax versus Nir Stent Study's long-term outcome

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Cited by 36 publications
(36 citation statements)
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“…However, while in vitro studies showed promise, an initial clinical study (using a tantalum stent substrate) resulted in a restenosis rate of 26.8%, again typical for bare metal stents with no major advantage evident [31]. A later iteration of the device utilized a stainless steel substrate, but in a comparison with a commercial stainless steel stent, the silicon carbide again failed to show a restenosis advantage over stainless steel [32]. So what appears to have been a well-investigated strategy again failed to live up to expectations and became another coating casualty in the pre-drugeluting stent era.…”
Section: Silicon Carbide and The Semiconductor Theorymentioning
confidence: 96%
“…However, while in vitro studies showed promise, an initial clinical study (using a tantalum stent substrate) resulted in a restenosis rate of 26.8%, again typical for bare metal stents with no major advantage evident [31]. A later iteration of the device utilized a stainless steel substrate, but in a comparison with a commercial stainless steel stent, the silicon carbide again failed to show a restenosis advantage over stainless steel [32]. So what appears to have been a well-investigated strategy again failed to live up to expectations and became another coating casualty in the pre-drugeluting stent era.…”
Section: Silicon Carbide and The Semiconductor Theorymentioning
confidence: 96%
“…Let us consider the following three well-researched ceramics. While silicon carbide coatings have shown no evidence of advantage over bare metal stents [28], the iridium oxide stents have demonstrated encouraging initial results [29]. On the other hand, the performance of titanium nitride oxide coatings has been highly satisfactory both in animal [30] and clinical [31] studies and is available in the market (TITANOX TM from Hexacath, Rueil-Malmaison, France).…”
Section: Coronary Stentsmentioning
confidence: 99%
“…The release of nickel, chromium, and molybdenum ions from 316LSS stent may trigger local immune response and inflammatory reactions, which may in turn induce intimal hyperplasia and in-stent restenosis ( Ref 2,5). The use of a protective film is a viable approach to mitigate excessive corrosion and it also combines the desirable characteristics of different materials ( Ref 6,7). In recent years, synthesizing bioceramic film on stent surface has been attracting considerable attention, since the good mechanical properties of metals and good chemical stability of ceramic films can be combined.…”
Section: Introductionmentioning
confidence: 99%