Comparison of a low carbohydrate–low fiber diet and a moderate carbohydrate–high fiber diet in the management of feline diabetes mellitus

Bennett, Nicole; Greco, Deborah S.; Peterson, Mark E.; Kirk, Claudia A.; Mathes, Mark; Fettman, Martin J.

doi:10.1016/j.jfms.2005.08.004

Cited by 103 publications

(98 citation statements)

References 31 publications

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“…Current recommendations for the management of type II diabetes and obesity include an increase in dietary fiber intake. Dietary fiber's viscose and fibrous structure can control the release of glucose with time in the blood, thus helping in the proper control and management of diabetes mellitus and obesity (Bennett et al 2006). …”

Section: Obesity and Diabetesmentioning

confidence: 99%

An Overview of the Recent Developments on Fructooligosaccharide Production and Applications

Dominguez

Rodrigues

Lima

et al. 2013

Food Bioprocess Technol

137

108

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Over the past years, many researchers have suggested that deficiencies in the diet can lead to disease states and that some diseases can be avoided through an adequate intake of relevant dietary components. Recently, a great interest in dietary modulation of the human gut has been registered. Prebiotics, such as fructooligosaccharides (FOS), play a key role in the improvement of gut microbiota balance and in individual health. FOS are generally used as components of functional foods, are generally regarded as safe (generally recognized as safe status-from the Food and Drug Administration, USA), and worth about 150€ per kilogram. Due to their nutrition-and health-relevant properties, such as moderate sweetness, low carcinogenicity, low calorimetric value, and low glycemic index, FOS have been increasingly used by the food industry. Conventionally, FOS are produced through a two-stage process that requires an enzyme production and purification step in order to proceed with the chemical reaction itself. Several studies have been conducted on the production of FOS, aiming its optimization toward the development of more efficient production processes and their potential as food ingredients. The improvement of FOS yield and productivity can be achieved by the use of different fermentative methods and different microbial sources of FOSproducing enzymes and the optimization of nutritional and culture parameter; therefore, this review focuses on the latest progresses in FOS research such as its production, functional properties, and market data.

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Section: Obesity and Diabetesmentioning

confidence: 99%

An Overview of the Recent Developments on Fructooligosaccharide Production and Applications

Dominguez

Rodrigues

Lima

et al. 2013

Food Bioprocess Technol

137

108

View full text Add to dashboard Cite

show abstract

“…Diabetic remission is hypothesized to occur when pancreatic β cells recover from the suppressive effects of hyperglycemia and are able to secrete sufficient insulin to maintain euglycemia 2, 3, 4. The probability of diabetic remission is likely increased with institution of early, effective glycemic control, and remission rates >80% are reported in newly diagnosed diabetic cats managed using long‐acting insulin1 and low carbohydrate diets 5, 6…”

mentioning

confidence: 99%

Glycemic Status and Predictors of Relapse for Diabetic Cats in Remission

Gottlieb¹,

Rand

Marshall³

et al. 2014

Veterinary Internal Medicne

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BackgroundIt is unknown if diabetic cats in remission have persistent abnormalities of glucose metabolism and should be considered prediabetic, or have normal glucose tolerance.ObjectiveTo characterize glycemic status of diabetic cats in remission and to determine predictors of relapse.AnimalsA total of 21 cats in diabetic remission and 28 healthy control cats.MethodsAt a median of 107 days after remission, screening blood glucose concentration was measured on entry to the clinic. After a 24‐hour fast in hospital, fasting blood glucose, fructosamine and feline pancreatic lipase concentrations were measured, and 3 hours later, a simplified IV glucose tolerance test (1 g glucose/kg) performed. Twenty cats were monitored for relapse for at least 9 months.ResultsOf the 21 cats in remission, 19% (4/21) had impaired fasting glucose concentration and 76% (16/21) had impaired glucose tolerance. Of cats followed up for 9 months after testing, 30% (6/20) had relapsed and required insulin treatment. Fasting blood glucose concentration ≥7.5 mmol/L (≥135 mg/dL) (odds ratio [OR] = 12.8) and severely impaired glucose tolerance (≥5 hours to return to <6.5 mmol/L or <117 mg/dL; OR = 15.2) were significantly associated with relapse. Blood glucose concentration >14 mmol/L; 252 mg/dL at 3 hours was significantly associated with relapse (OR = 10.1).Conclusion and Clinical ImportanceMost cats in diabetic remission have impaired glucose tolerance and a minority have impaired fasting glucose concentration and should be considered prediabetic. More severe glucose intolerance and impaired fasting glucose concentration are predictors of relapse. Ongoing glucose monitoring of diabetic cats in remission is recommended.

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“…High-protein, low-carbohydrate diets reduce postprandial hyperglycemia, but also decrease the overall insulin requirement, possibly indicating a reduced demand on the β-cells to produce insulin in diabetic cats [5]. A lowcarbohydrate diet may aid in glycemic control in diabetic cats by decreasing hyperglycemia and markedly decrease the in insulin dose [13,27].…”

Section: Discussionmentioning

confidence: 99%

Impact of Commercially Available Diabetic Prescription Diets on Short-Term Postprandial Serum Glucose, Insulin, Triglyceride and Free Fatty Acid Concentrations of Obese Cats

et al. 2013

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ABSTRACT. Diet therapy is an important treatment component available for obese cats. In this study, the impact of four commercially available prescription diet regimens (1 for general use and 3 aimed at treating obesity and diabetes mellitus (DM)) on short-term postprandial serum glucose, insulin, triglyceride and nonesterified fatty acid (NEFA) concentrations was investigated with five obese cats. The diet regimens used were as follows: C/D dry (general use: moderate protein, moderate fat, high carbohydrate and low fiber), M/D dry (DM: high protein, high fat, low carbohydrate and high fiber), W/D dry (DM: high protein, low fat, high carbohydrate and high fiber) and Diabetic dry (DM: high protein, low fat, low carbohydrate and high fiber). A significant reduction (10-13%) in postprandial glucose (area under the curve; AUC) was observed with the M/D and Diabetic diets, which both contained lower concentrations of carbohydrates than the C/D diet. An accompanying significant reduction (30-36%) in postprandial insulin AUC was also observed with the three DM diets, which all had higher amounts of fiber, as compared with the C/D diet. Lastly, a significant increase (32-65%) in postprandial NEFA AUC was observed with the M/D and Diabetic diets as compared with the C/D diet. Therefore, dietary amounts of carbohydrates and fiber, as opposed to protein content or dietary fat, appear to have a very significant impact on postprandial glycemia and subsequent insulin requirement levels in obese cats. In addition, dietary amounts of carbohydrates may also impact lipid metabolism in obese cats.

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Comparison of a low carbohydrate–low fiber diet and a moderate carbohydrate–high fiber diet in the management of feline diabetes mellitus

Cited by 103 publications

References 31 publications

An Overview of the Recent Developments on Fructooligosaccharide Production and Applications

An Overview of the Recent Developments on Fructooligosaccharide Production and Applications

Glycemic Status and Predictors of Relapse for Diabetic Cats in Remission

Impact of Commercially Available Diabetic Prescription Diets on Short-Term Postprandial Serum Glucose, Insulin, Triglyceride and Free Fatty Acid Concentrations of Obese Cats

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