Comparison of 64-Slice Multidetector Computed Tomography With Spectral Analysis of Intravascular Ultrasound Backscatter Signals for Characterizations of Noncalcified Coronary Arterial Plaques

Choi, Byoung‐Joo; Kang, D.R.; Tahk, Seung‐Jea; Choi, So–Yeon; Yoon, Myeong‐Ho; Lim, Hong–Seok; Kang, Soo-Jin; Yang, Hyoung‐Mo; Park, Jin-Sun; Zheng, Mingri; Hwang, Gyo‐Seung; Shin, Joon-Han

doi:10.1016/j.amjcard.2008.05.060

Cited by 56 publications

(30 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Previous studies evaluating the utility of cardiac CT to characterise atherosclerotic plaque, using intravascular ultrasound (IVUS) or histology as a reference standard, reported that 16-or 64-slice CT may have the potential to determine the composition of coronary or carotid plaque [6,17,24,25]. Recently, the composition of plaques on CT was elegantly shown to be predictive for outcome [16].…”

Section: Methodological Aspectsmentioning

confidence: 98%

“…The composition of atherosclerotic plaque was assessed by using the Plaque SW version 4.0.2 (Extended Brilliance Workspace 4.0, Philips Medical Systems) with the aim to differentiate between calcified and non-calcified components on CT images according to regional attenuation values [6,16,17]. For each coronary artery the vessel lumen and wall were automatically registered, and after the identification of each lesion the boundaries were manually edited if necessary.…”

Section: Analysis Of Coronary Plaque Volume and Compositionmentioning

confidence: 99%

See 1 more Smart Citation

Quantitative assessment of stenosis severity and atherosclerotic plaque composition using 256-slice computed tomography

et al. 2010

View full text Add to dashboard Cite

show abstract

Section: Methodological Aspectsmentioning

confidence: 98%

Section: Analysis Of Coronary Plaque Volume and Compositionmentioning

confidence: 99%

Quantitative assessment of stenosis severity and atherosclerotic plaque composition using 256-slice computed tomography

et al. 2010

View full text Add to dashboard Cite

show abstract

“…In addition, the assessment of the entire coronary tree requires a 3-vessel catheter-based interrogation, which may involve additional risks for the patients [21] . In this regard, CCTA would be a valuable non-invasive alternative to IVUS, especially in light of the good correlation of the 2 techniques in terms of plaque composition assessment [14,32,38,[47][48][49] .…”

Section: Virtual Histology-intravascular Ultrasoundmentioning

confidence: 99%

Assessment of coronary artery disease using coronary computed tomography angiography and biochemical markers

Gitsioudis

Katus

Korosoglou

2014

WJC

View full text Add to dashboard Cite

Chronic inflammatory mechanisms in the arterial wall lead to atherosclerosis, and include endothelial cell damage, inflammation, apoptosis, lipoprotein deposition, calcification and fibrosis. Cardiac computed tomography angiography (CCTA) has been shown to be a promising tool for non-invasive assessment of theses specific compositional and structural changes in coronary arteries. This review focuses on the technical background of CCTA-based quantitative plaque characterization. Furthermore, we discuss the available evidence for CCTA-based plaque characterization and the potential role of CCTA for risk stratification of patients with coronary artery disease.© 2014 Baishideng Publishing Group Inc. All rights reserved.Key words: Atherosclerotic plaque composition; Quantification analysis; Multi-slice cardiac computed tomography; Biomarkers Core tip: This review gives an overview of the current status of noninvasive assessment of coronary artery disease (CAD) and the ability of cardiac computed tomography angiography (CCTA) and cardiac biomarkers for the diagnostic classification and risk stratification of patients with suspected and known CAD. Since all techniques described herein are available in the clinical routine and are associated with an acceptable time spent the translation to the clinical realm appears promising. Focusing on CCTA-based quantitative plaque characterization we herein present the (1) available evidence; (2) comparison with other techniques of plaque characterization; and (3) the value of "bio-imaging" for the risk stratification of patients with CAD.Gitsioudis G, Katus HA, Korosoglou G. Assessment of coronary artery disease using coronary computed tomography angiography and biochemical markers.

show abstract

“…1, multidector CT (MDCT) has shown promise when compared to intravascular ultrasound (IVUS) at detecting soft, intermediate, and calcified plaques [31]. However, these data have since been challenged, given the fact that there is substantial overlap in the characteristics of calcified and non-calcified plaques with respect to the amount of necrotic core present [32][33][34]. Knollman demonstrated that MDCT correlated well with histopathologic analysis of total plaque area (r=0.73, P< 0.0001) and calcified plaque area (r=0.83, P<0.0001), while measurements of non-calcified plaque area (r=0.53, P<0.0001) and lipid core size (r=0.43; P<0.0001) did not correlate as well.…”

Section: Cardiac Computed Tomography (Ct)mentioning

confidence: 98%

Vulnerable Plaque Imaging—Current Techniques

Hilty

Steinberg

2009

J. of Cardiovasc. Trans. Res.

View full text Add to dashboard Cite

Tremendous progress has been made over the past 30 years in the management of plaque rupture and acute coronary thrombosis. With the advent of new interventional cardiac techniques and concomitant advances in medical therapy, there has been a steady decline in cardiovascular mortality. Acute coronary syndromes, especially ST elevation myocardial infarction, still occur frequently and are associated with significant morbidity and mortality. As these events typically occur in lesions without severe pre-existing stenosis, interest has increased in identifying these "vulnerable plaques" and ultimately preventing myocardial infarction. Recently, several new invasive and non-invasive modalities have been developed to identify and better characterize vulnerable plaque. This review will cover the pathobiology of vulnerable plaque, current invasive and non-invasive imaging techniques, tissue characterization, and future applications of this exciting technology.

show abstract

Comparison of 64-Slice Multidetector Computed Tomography With Spectral Analysis of Intravascular Ultrasound Backscatter Signals for Characterizations of Noncalcified Coronary Arterial Plaques

Cited by 56 publications

References 12 publications

Quantitative assessment of stenosis severity and atherosclerotic plaque composition using 256-slice computed tomography

Quantitative assessment of stenosis severity and atherosclerotic plaque composition using 256-slice computed tomography

Assessment of coronary artery disease using coronary computed tomography angiography and biochemical markers

Vulnerable Plaque Imaging—Current Techniques

Contact Info

Product

Resources

About