Comparison between whole-body MRI with diffusion-weighted imaging and PET/CT in staging newly diagnosed FDG-avid lymphomas.

Albano, Domenico; Patti, Caterina; Grutta, Ludovico La; Agnello, Francesco; Grassedonio, Emanuele; Mulè, Antonino; Cannizzaro, G; Ficola, Umberto; Lagalla, Roberto; Midiri, Massimo; Gallucci, M.

doi:10.1016/j.ejrad.2015.12.006

Cited by 68 publications

(49 citation statements)

References 31 publications

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“…Among other malignant tumors in our series, those with lower ADC values were lymphomas and multiple myelomas. As demonstrated by previous studies, bone lymphomas have very low mADC values due to the high cellularity and elevated nuclear‐to‐cytoplasm ratio of the tumor causing lower diffusivity of water molecules in localizations of disease …”

Section: Discussionmentioning

confidence: 72%

Solid bone tumors of the spine: Diagnostic performance of apparent diffusion coefficient measured using diffusion‐weighted MRI using histology as a reference standard

Pozzi

Albano

Messina

et al. 2017

Magnetic Resonance Imaging

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Section: Discussionmentioning

confidence: 72%

Solid bone tumors of the spine: Diagnostic performance of apparent diffusion coefficient measured using diffusion‐weighted MRI using histology as a reference standard

Pozzi

Albano

Messina

et al. 2017

Magnetic Resonance Imaging

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“…The emerging role of whole-body magnetic resonance imaging for disease monitoring in NHL Over the last years, several studies have demonstrated the good reliability of whole-body magnetic resonance imaging (WB-MRI) for lymphoma staging, mainly using 18 F-FDG-PET/CT as the reference standard [24][25][26][27]. WB-MRI enables avoiding radiation exposure and intravenous contrast agent administration, allowing the evaluation of all potential lymphomatous sites through morphological and functional sequences ( Figs.…”

Section: Imaging Monitoring and Wwmentioning

confidence: 99%

Whole body magnetic resonance in indolent lymphomas under watchful waiting: The time is now

et al. 2017

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The indolent non-Hodgkin lymphomas (i-NHLs) are characterised by 'indolent' clinical behaviour with slow growth and prolonged natural history. The watchful waiting (WW) strategy is a frequently employed treatment option in these patients. This implies a strict monitoring by imaging examinations, including 18F-fluorodeoxyglucose-positron emission tomography/computed tomography (18F-FDG-PET/CT) and CT. A major concern is radiation exposure due to regularly monitoring by conventional imaging procedures. Several studies have demonstrated the reliability of whole-body magnetic resonance imaging (WB-MRI) for lymphoma staging. WB-MRI could be useful for active surveillance in iNHLs providing the suspect of disease progression that can be then confirmed by additional diagnostic procedures, including 18F-FDG-PET/CT. The directive 2013/59 by the European Union claims that if a radiation-free imaging technique allows obtaining the same diagnostic results, it should be invariably used.In this setting, WB-MRI may be considered a reasonable option in i-NHLs under WW, replacing imaging modalities that cause exposure to ionising radiations. This will help to reduce the cancer risk in i-NHL patients for whom chemo-/radiotherapy remain the usual treatment options following the usually long WW phase. The scientific community should raise the awareness of the risk of ionising radiations in i-NHLs and the emphasise the need for establishing the proper place of WB-MRI in lymphoma imaging. Key Points• Watchful waiting is a reasonable option in patients with indolent non-Hodgkin lymphomas.• Imaging is crucial to monitor patients with indolent nonHodgkin lymphomas.• CT and 18 F-FDG-PET/CT are commonly used, implying a substantial radiation exposure.• WB-MRI is highly reliable in lymphoma staging.• WB-MRI may be considered to monitor indolent nonHodgkin lymphomas under watchful waiting.

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“…Especially when taking into account that during treatment repeated imaging is required, children with Hodgkin lymphoma might be at increased risk of radiation-induced malignancies later in life [3, 6]. In recent literature, both whole-body MRI and FDG-PET/MRI have been investigated as alternatives to FDG-PET/CT for staging (adult) Hodgkin lymphoma, in order to reduce radiation dose to the patient [7–11]. …”

Section: Introductionmentioning

confidence: 99%

Imaging features of extranodal involvement in paediatric Hodgkin lymphoma

et al. 2018

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Comparison between whole-body MRI with diffusion-weighted imaging and PET/CT in staging newly diagnosed FDG-avid lymphomas.

Cited by 68 publications

References 31 publications

Solid bone tumors of the spine: Diagnostic performance of apparent diffusion coefficient measured using diffusion‐weighted MRI using histology as a reference standard

Solid bone tumors of the spine: Diagnostic performance of apparent diffusion coefficient measured using diffusion‐weighted MRI using histology as a reference standard

Whole body magnetic resonance in indolent lymphomas under watchful waiting: The time is now

Imaging features of extranodal involvement in paediatric Hodgkin lymphoma

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