Comparison between Three-Dimensional Navigator-Gated Whole-Heart MRI and Two-Dimensional Cine MRI in Quantifying Ventricular Volumes

Abstract

ObjectiveTo test whether the method utilizing three-dimensional (3D) whole-heart MRI has an additional benefit over that utilizing conventional two-dimensional (2D) cine MRI in quantifying ventricular volumes.Materials and MethodsIn 110 patients with congenital heart disease, a navigator-gated, 3D whole-heart MRI during end-systole (ES) and end-diastole (ED), 2D short-axis cine MRI, and phase contrast MRI of the great arteries were acquired. Ventricular volumes were measured by using a 3D threshold-based segmentation for 3D whole-heart MRI and by using a simplified contouring for 2D cine MRI. The cardiac trigger delays of 3D whole-heart MRI were compared with those of a 2D cine MRI. The stroke volumes calculated from the ventricular volumes were compared with the arterial flow volumes, measured by phase contrast MRI.ResultsThe ES and ED trigger delays of whole-heart MRI were significantly less than cine MRI for both the left ventricle (−16.8 ± 35.9 ms for ES, −59.0 ± 90.4 ms for ED; p < 0.001) and the right ventricle (−58.8 ± 30.6 ms for ES, −104.9 ± 92.7 ms for ED; p < 0.001). Compared with the arterial flow volumes, 2D cine MRI significantly overestimated the left ventricular stroke volumes (8.7 ± 8.9 mL, p < 0.001) and the 3D whole-heart MRI significantly underestimated the right ventricular stroke volumes (−22.7 ± 22.9 mL, p < 0.001).ConclusionThree-dimensional whole-heart MRI is often subject to early timing of the ED phase, potentially leading to the underestimation of the right ventricular stroke volumes.

Volumetric Severity Assessment of Ebstein Anomaly Using Three-Dimensional Cardiac CT: A Feasibility Study

“…Other researchers have suggested that volumetric quantification using a 3D imaging modality may expedite a better understanding of the relationship between the RV status and disease severity in Ebstein anomaly [4,5]. In particular, the use of 3D threshold-based segmentation could eliminate the time-consuming and reader-dependent manual endocardial tracings for ventricular volumetry as demonstrated in previous studies [7,9]. The threshold-based approach was reported to show high reproducibility with an inter-measurement difference of 1.0±1.1%, and intraclass correlation coefficient of 1.0 [24].…”

“…However, cine MRI is limited by its ability to accurately segment the malformed tricuspid valve and RV endocardial borders because of its two-dimensional (2D) nature [3][4][5][6].Cardiac MRI is generally limited by its long examination time, which often requires conscious sedation or general anesthesia. In addition, the threshold-based segmentation results of threedimensional (3D) whole-heart MRI data are often influenced by inhomogeneous signal intensity and imaging artifacts [7]. In contrast, cardiac CT is increasingly used to evaluate congenital cc This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/bync/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.Objective: The purpose of this study was to demonstrate the feasibility of using cardiac CT to perform volumetric severity assessment of the Ebstein anomaly.…”

“…Cardiac MRI is generally limited by its long examination time, which often requires conscious sedation or general anesthesia. In addition, the threshold-based segmentation results of threedimensional (3D) whole-heart MRI data are often influenced by inhomogeneous signal intensity and imaging artifacts [7]. In contrast, cardiac CT is increasingly used to evaluate congenital cc This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/bync/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.…”

Guideline for Cardiovascular Magnetic Resonance Imaging from the Korean Society of Cardiovascular Imaging—Part 1: Standardized Protocol

“…Herein, we offer a practical standard CMR protocol for beginners designed to be easy to follow and implement. This protocol guideline is based on previously reported CMR guidelines [1][2][3][4][5][6][7][8][9] and includes sequence terminology used by vendors, essential MR physics [10][11][12][13][14][15][16][17], imaging planes [2,18], field strength considerations [19][20][21][22][23][24][25], MRI-conditional devices [10,20,[26][27][28][29][30][31][32][33], drugs for stress tests [34], various CMR modules [16,[35][36][37][38][39][40][41][42][43][44][45]…”

Guidelines for Cardiovascular Magnetic Resonance Imaging from the Korean Society of Cardiovascular Imaging—Part 2: Interpretation of Cine, Flow, and Angiography Data

“…The anatomy and cardiac function section includes cine magnetic resonance imaging (MRI), flow imaging, and angiography. Cine MRI has been known as the gold standard for ventricular functional analysis and, with recent advances in MRI and CT, studies comparable to cine MRI have been reported [4][5][6]. In addition, studies have been carried out to estimate the prognosis of the disease by measuring myocardial strain using cine MRI, and to evaluate the left atrial volume in patients with atrial fibrillation by using three-dimensional (3D) CMR [7][8][9].…”