Abstract:ACCORDING to Becker, Pyle, and Drews (1959) the instillation of miotics into glaucomatous eyes may be followed by an increase in the tonographically calculated coefficient of aqueous outflow, together with lowering of intra-ocular pressure. Although there is a well-accepted clinical grading of the various miotics by "strength" from pilocarpine at the lower end to the powerful cholinesterase inhibitors at the upper, our knowledge is still surprisingly scanty regarding exact dose-response relationships. The stud… Show more
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