Comparison between routine cylindrical cerebral aneurysm volume approximation and three-dimensional volume measurements in experimental aneurysms

Erhardt, Salome; Marbacher, Serge; Neuschmelting, Volker; Coluccia, Daniel; Remonda, Luca; Fandiño, Javier

doi:10.1179/1743132813y.0000000316

Cited by 4 publications

(4 citation statements)

References 21 publications

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“…Measurements of aneurysms in terms of volume is attractive because of its potential to provide a more sensitive and comprehensive assessment of change. 18 Several software-based methods of volume measurement have been implemented on CTA images. 14 CE-MRA has advantages in the serial monitoring of untreated UIAs because there is no radiation (as in CTA) or arterial catheterizationrelated risks (as in conventional angiography).…”

Section: Discussionmentioning

confidence: 99%

A Volumetric Metric for Monitoring Intracranial Aneurysms: Repeatability and Growth Criteria in a Longitudinal MR Imaging Study

Liu

Haraldsson

Wang

et al. 2021

AJNR Am J Neuroradiol

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BACKGROUND AND PURPOSE:The reliability of contrast-enhanced MRA in monitoring serial volumetric changes of unruptured intracranial aneurysms has not been established. We aimed to determine the coefficient of variance of contrast-enhanced MRA in measuring aneurysm volumes, thus establishing criteria for aneurysm growth and permitting identification of variables predictive of growth.MATERIALS AND METHODS: Aneurysm volumes were measured from serial contrast-enhanced MRA studies of patients with untreated intracranial aneurysms who underwent .2 sequential MR imaging evaluations. After coregistering all sequential studies in 3D space for each aneurysm and signal intensity normalization, aneurysm volume was determined across all time points. A linear mixed effects model was built to estimate the coefficient of variance of the measurement as well as to determine predictive variables. Growth was defined as relative growth exceeding 2 times the measurement coefficient of variance (sudden growth, as 4 times the coefficient of variance).RESULTS: A total of 95 patients with 112 aneurysms were included (5.9 scans during 4.0 years on average, 616 scan measurements in total). The coefficient of variance was 5.5% of the aneurysm volume, and the relative growth rate was dependent on the location: anterior cerebral artery, 4.52% per year; vertebral artery, 2.46% per year; middle cerebral artery, 2.74% per year; basilar artery, 2.36% per year; internal carotid artery, 1.14% per year. Thirty-six of 112 (32%) aneurysms were characterized as growing, and 11/36 of them had an episode of sudden growth. CONCLUSIONS:Volume measurement of unruptured intracranial aneurysms by contrast-enhanced MRA seems a reliable metric for tracking the growth trajectory of aneurysms. Furthermore, the aneurysm growth rate differs among different locations.

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Section: Discussionmentioning

confidence: 99%

A Volumetric Metric for Monitoring Intracranial Aneurysms: Repeatability and Growth Criteria in a Longitudinal MR Imaging Study

Liu

Haraldsson

Wang

et al. 2021

AJNR Am J Neuroradiol

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“…In this study we employed a new strategy to quantify aneurysm volume and neck surface area ( Figure 1 ). Quantification of aneurysm volume via a formula has been shown to be inaccurate and is inferior to 3D volume rendering [ 13 ]. We reconstructed aneurysm volume using thin cut CT DICOM images ( Figure 1 A).…”

Section: Discussionmentioning

confidence: 99%

“…Several factors have been correlated with increased risk for treatment failure, namely aneurysm volume, residual uncoiled volume, coil packing density, and Raymond-Roy classification (RRC) [ 10 , 11 , 12 ]. These metrics rely on the accuracy of aneurysm volume estimation, which considering the complex and varied shapes of aneurysms, often requires careful assessment rather than a simple formulaic calculation [ 13 ]. Previous models have used aneurysm diameter or packing density calculated by a formula to assess recanalization [ 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

Three-dimensional aneurysm volume measurements show no correlation between coil packing density and recurrence

Thaçi

Nuño

Varshneya

et al. 2020

Heliyon

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Objective Endovascular treatment is the mainstay therapy for brain aneurysms. About 15% of patients need re-treatment within six months due to early recanalization. In this study, we investigate risk factors associated with treatment failure. Methods This retrospective cohort study includes endovascularly treated aneurysm cases between July 2012 and December 2015 at the University of California Davis Medical Center with pre-treatment and early post-treatment imaging. Thin cut 3D aneurysm volume rendering was used for morphologic analyses. Univariate and bivariate analyses were conducted to evaluate differences between patients and clinical factors by treatment failure. Results Of the 50 patients who met the inclusion criteria, 41 (82.0%) were female, with an average age of 61 years. Most aneurysms were on the anterior communicating artery (40%) or posterior communicating artery (22.0%), and 34 (68%) aneurysms were ruptured. Early treatment failure was observed in 14 (28.0%) of endovascularly treated patients. Raymond-Roy class (RRC) was significantly associated with treatment failure (p = 0.0052), with 10 out of the 14 cases (71.4%) with early recanalization having an RRC of 3. Coil packing density did not associate with aneurysm recanalization (p = 0.61). Conclusion In our single institution series, patient characteristics, aneurysm characteristics, or coil packing density did not affect early aneurysm recanalization. RRC was the best predictor of early recanalization; however, further confirmation with additional studies are required. Although this study focused on early treatment failure, late recanalization has been shown with longer follow up. Further investigation into factors associated with late treatment failure will need further investigation. New intrasaccular devices and flow diverters will also likely play a role in reducing recurrence in the future as these treatments gain usage.

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“…[ 127 ] 2014 X Surgical Swines Saccular X Liu Y. [ 128 ] 2014 X Surgical Rabbits Saccular and fusiform X Donzelli R. [ 129 ] 2014 X Surgical Rabbits Saccular X Erhardt S. [ 130 ] 2014 X Surgical Rabbits Saccular X Cebral J.R. [ 131 ] 2014 X Surgical Rabbits Saccular X X …”

Section: Methodsmentioning

confidence: 99%

Imaging of intracranial aneurysms in animals: a systematic review of modalities

et al. 2023

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Intracranial aneurysm (IA) animal models are paramount to study IA pathophysiology and to test new endovascular treatments. A number of in vivo imaging modalities are available to characterize IAs at different stages of development in these animal models. This review describes existing in vivo imaging techniques used so far to visualize IAs in animal models. We systematically searched for studies containing in vivo imaging of induced IAs in animal models in PubMed and SPIE Digital library databases between 1 January 1945 and 13 July 2022. A total of 170 studies were retrieved and reviewed in detail, and information on the IA animal model, the objective of the study, and the imaging modality used was collected. A variety of methods to surgically construct or endogenously induce IAs in animals were identified, and 88% of the reviewed studies used surgical methods. The large majority of IA imaging in animals was performed for 4 reasons: basic research for IA models, testing of new IA treatment modalities, research on IA in vivo imaging of IAs, and research on IA pathophysiology. Six different imaging techniques were identified: conventional catheter angiography, computed tomography angiography, magnetic resonance angiography, hemodynamic imaging, optical coherence tomography, and fluorescence imaging. This review presents and discusses the advantages and disadvantages of all in vivo IA imaging techniques used in animal models to help future IA studies finding the most appropriate IA imaging modality and animal model to answer their research question.

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Comparison between routine cylindrical cerebral aneurysm volume approximation and three-dimensional volume measurements in experimental aneurysms

Cited by 4 publications

References 21 publications

A Volumetric Metric for Monitoring Intracranial Aneurysms: Repeatability and Growth Criteria in a Longitudinal MR Imaging Study

A Volumetric Metric for Monitoring Intracranial Aneurysms: Repeatability and Growth Criteria in a Longitudinal MR Imaging Study

Three-dimensional aneurysm volume measurements show no correlation between coil packing density and recurrence

Imaging of intracranial aneurysms in animals: a systematic review of modalities

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