Comparison between response surface methodology and genetic algorithm to optimize lactic acid production by Lactobacillus rhamnosus and Lactobacillus acidophilus under ultrasonic pretreatment
Abstract:This work compared response surface methodology (RSM) and genetic algorithm (GA) analysis to optimize the lactic acid content by Lactobacillus rhamnosus PTCC 1637 and Lactobacillus acidophilus PTCC 1643 in a medium based of date syrup. Three parameters including concentrations of sucrose (10 and 20% (w/w)) and yeast extract (1, 2 and 3% (w/w)) along with different amplitudes of ultrasound (30 kHz, 25 and 50%) were investigated in terms of their impacts on both viable cell counts and lactic acid production. Reg… Show more
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