Comparison between MRI Findings and Histopathological Diagnosis in the Evaluation of Posterior Fossa Tumors in Pediatric Patients

Abstract

Background: Conventional radiography and CT scan failed to reveal the posterior fossa tumors which not accurately show tumors behind bone. MRI is currently recognized as the optimal screening technique for detection of posterior fossa tumors. We tried to compare the MRI findings with the histopathological findings of different types of posterior fossa tumors in pediatric patients. Histopathological reports were regarded as the gold standard.
 Objective: To assess the diagnostic effectiveness of MRI in detection of posterior cranial fossa tumors in pediatric patients.
 Methods: This cross sectional study was carried out in the department of Neurosurgery, DMCH, NINS and some private hospitals in Dhaka from March, 2012 to November, 2013. Purposive sampling technique was applied and 34 cases were included in the study. Data were collected by specially designed questionnaire and analysed by SPSS.
 Results: Out of 34 cases, MRI failed to match with the histopathological diagnosis only in 2 cases. One case was diagnosed as cerebellar astrocytoma by MRI, histopathology proved it brain abscess. In another case, MRI diagnosed as ependymoma but histopathology revealed medulloblastoma.
 Conclusion: It can be concluded That MRI is accepted as the most effective imaging modality in the diagnosis of paediatric posterior fossa tumors. T1WI, T2WI, FLAIR, axial, sagittal, coronal and T1WI post contrast sequences permit confident diagnosis and localization of the pediatric posterior fossa tumor.
 Bang. J Neurosurgery 2020; 10(1): 62-66

Diagnostic Validity of Magnetic Resonance Imaging for the Detection of Ependymoma among Bangladeshi Children

“…Ependymoma is the 3 rd most common pediatric brain tumor and infratentorial ependymoma occurs in 60.0% to 73.0% patients 2 and more than 90.0% cases of posterior fossa tumors located in the 4th ventricle 3 . Solid portions of ependymoma typically are iso intense to hypo intense relative to white matter on short recovery time/echo time (TR/TE) T1WI 4 . The tumor is hyper intense to white matter on long TR/TE T2-WI and as many as 50.0% cases of ependymomas demonstrate signal heterogenicity which may indicate calcification, necrosis, methemoglobin, hemosiderin 5 .…”