Comparison between modified skin prick test with standardized allergen extracts and Phazet

Chanal, I.; Horst, Manfred; Segalen, C.; Dreborg, Sten; Michel, F. B.; Bousquet, Jean

doi:10.1016/0091-6749(88)90093-0

Cited by 26 publications

(11 citation statements)

References 11 publications

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“…Serum‐specific IgE levels were measured using the CAP System ® (Pharmacia Diagnostics) in a central laboratory (16) (except for the Australian centre). The allergen‐coated Phazet ® (Pharmacia Diagnostics) was used for skin testing (17). A histamine positive control and a saline negative control were also skin tested to reduce false positives and negatives.…”

Section: Methodsmentioning

confidence: 99%

Original article: Assessing skin prick tests reliability in ECRHS‐I

Bousquet

Chatzi

Jarvis

et al. 2008

Allergy

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Section: Methodsmentioning

confidence: 99%

Original article: Assessing skin prick tests reliability in ECRHS‐I

Bousquet

Chatzi

Jarvis

et al. 2008

Allergy

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“…The validity of this test has been previously evaluated (2). The criterion for inclusion in the study was a positive skin test for Dermatophagoides pteronyssinus.…”

Section: Methodsmentioning

confidence: 99%

Can mite‐specific IgE be used as a surrogate for mite exposure?

Lovinfosse

Charpin

Dornelas

et al. 1994

Allergy

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Several epidemiologic studies suggest that in mite-sensitive patients symptoms are dependent upon mite-exposure level. However, in clinical practice, it si not easy to measure major mite allergens. In contrast, assay of specific IgE antibodies can be done routinely. Thus, we wanted to compare, in a group of 40 mite-sensitive patients, the levels of mite-specific IgE (measured by RAST grade 0-6) and the level of mite group I allergen in mattresses (measured in micrograms/g house dust). The correlation coefficient between both variables was highly significant (P = 0.001). Subjects with a RAST grade of 3 or more had a 77% probability of being exposed to high (i.e., > 10 micrograms/g dust) mite allergen level. In contrast, subjects with RAST grades 0, 1, or 2 had a 77% probability of not being exposed to such high levels. Thus, measurement of serum mite-specific IgE level could be used in routine prediction of mite exposure.

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“…The modified skin prick test introduced by Pepys (1163) is the current reference method. Puncture tests with various devices were introduced to decrease the variability of skin prick tests (1164)(1165)(1166)(1167)(1168)(1169)(1170)(1171)(1172)(1173). With a trained investigator, they are highly reproducible (1171)(1172)(1173).…”

Section: Skin Testsmentioning

confidence: 99%