Comparison Between Lipofilling and a Nonabsorbable Filler for Facial Wasting Rehabilitation in HIV-Positive Patients

Rauso, Raffaele; Curinga, Giuseppe; Santillo, Vincenzo; Corvo, G; Tartaro, Gianpaolo

doi:10.1097/scs.0b013e31822e5cf8

Cited by 16 publications

(15 citation statements)

References 30 publications

(13 reference statements)

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“…Lipofilling significantly improved facial esthetics, but evaluation at 48 weeks found that facial volume had decreased to baseline levels in all but one patient . However, as Rauso et al . later noted in 2011, the study by Negredo et al .…”

Section: Resultsmentioning

confidence: 87%

“…These included one RCT and eight observational 15 Lipofilling significantly improved facial esthetics, but evaluation at 48 weeks found that facial volume had decreased to baseline levels in all but one patient. 15 However, as Rauso et al 43 later noted in 2011, the study by Negredo et al 15 does not report on whether or not overfilling was performed. Overfilling is a technique used to overcorrect the defect in facial volume because studies have shown that some of the transferred fat will be lost.…”

Section: Silicone Oilmentioning

confidence: 99%

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Quality of life outcomes associated with treatment of human immunodeficiency virus (HIV) facial lipoatrophy

et al. 2016

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Facial lipoatrophy (FLA), characterized by a decrease in facial volume, has a high prevalence in patients with human immunodeficiency virus (HIV) infection treated with long-term highly active antiretroviral therapy (HAART). The social stigmatization that results from such changes in facial appearance has led some HIV patients to discontinue HAART. The use of fillers is one method of restoring facial volume. A critical outcome of treatment concerns the patient's quality of life (QoL). Although many studies have assessed patient satisfaction, as well as the social and psychological outcomes associated with the correction of HIV FLA, fewer studies have assessed QoL. We reviewed treatment options for HIV FLA with a specific focus on QoL outcomes. Our analysis revealed that the following treatments were associated with improvements in QoL: poly-l-lactic acid; calcium hydroxylapatite; hyaluronic acid; polyacrylamide gel; polyalkylamide gel; polymethylmethacrylate; silicone oil; and autologous fat transfer. The treatment of HIV FLA with these agents appears to improve QoL as assessed by various QoL instruments. Additional studies are required to identify a unifying QoL instrument to effectively assess longitudinal QoL outcomes and to compare treatment modalities.

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Section: Resultsmentioning

confidence: 87%

Section: Silicone Oilmentioning

confidence: 99%

Quality of life outcomes associated with treatment of human immunodeficiency virus (HIV) facial lipoatrophy

et al. 2016

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“…Lipofilling resulted in a better aesthetic outcome than PAAG in injections, especially by the ability to inject the autologous fat deeper than the synthetic filler. 135 Another study by Uzzan et al . showed similar results.…”

Section: Therapymentioning

confidence: 98%

“…134 However, recent studies have shown success with lipofilling for facial wasting. 135,136 In a clinical prospective study 23 HIV-infected patients suffering from FLA were treated either with lipofilling (14 patients) or with PAAG (9 patients). 135 Fat was harvested from lipohypertrophied areas such as the lower abdomen, mammary region and buffalo hump.…”

Section: Therapymentioning

confidence: 99%

Current treatment methods for combination antiretroviral therapy-induced lipoatrophy of the face

Kadouch

Rozelaar²,

Karim

et al. 2013

Int J STD AIDS

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Combination antiretroviral therapy (CART) reduces the mortality and morbidity in HIV-infected patients. However, facial lipoatrophy (FLA) is one of the well-known side-effects of this treatment and subsequently imposes major problems for HIV-infected patients. In the last decade, ample experience has been obtained with both local therapeutic options as well as possible systemic treatment options. Soft tissue fillers are a relatively simple and efficient treatment option for FLA. Especially, the biodegradable semi-permanent fillers combine a good effect with durability and an acceptable safety profile. The best way to prevent or restrict the development of FLA remains the exclusion of thymidine analogue nucleoside reverse-transcriptase inhibitors from the CART schedule.

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“…A prospective study assessed 23 HIV-positive patients with facial lipoatrophy who were randomized to undergo treatment with autologous fat transfer or Aquamid. 13 Follow-up visits were scheduled at 3, 6, and 12 months after initial evaluation to evaluate clinical efficacy. The primary endpoint in the study used the Global Aesthetic Improvement Scale, which was measured by the investigator 1 year after baseline.…”

Section: Clinical Efficacy Of Aquamidmentioning

confidence: 99%

Emerging permanent filler technologies: focus on Aquamid

Yamauchi¹

2014

CCID

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A plethora of soft tissue fillers have been developed within the past decade to correct the cutaneous changes that occur with photoaging. Such fillers, whether nonpermanent, semipermanent, or permanent, are widely used to fill undesired facial rhytides. In addition, fillers are employed to correct atrophy of the face as well as other parts of the body such as the dorsum of the hands through volumization and contouring. The extensive long-term safety outcomes reported with fillers and the ease with which they are administered make them an ideal choice to correct rhytides and to contour the face. However, as with any cosmetic procedure, in order to ensure high patient satisfaction and a safe outcome, proper training in injection techniques, the choice of the proper candidate, and awareness of potential adverse events are essential. This review article focuses on the permanent filler, Aquamid, which is composed of polyacrylamide hydrogel.

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Comparison Between Lipofilling and a Nonabsorbable Filler for Facial Wasting Rehabilitation in HIV-Positive Patients

Cited by 16 publications

References 30 publications

Quality of life outcomes associated with treatment of human immunodeficiency virus (HIV) facial lipoatrophy

Quality of life outcomes associated with treatment of human immunodeficiency virus (HIV) facial lipoatrophy

Current treatment methods for combination antiretroviral therapy-induced lipoatrophy of the face

Emerging permanent filler technologies: focus on Aquamid

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