Comparison Between Hybrid Direct Aperture Optimized Intensity-Modulated Radiotherapy and Forward Planning Intensity-Modulated Radiotherapy for Whole Breast Irradiation

Descovich, M.; Fowble, Barbara; Bevan, Alison; Schechter, Naomi R.; Park, Catherine; Xia, Peng

doi:10.1016/j.ijrobp.2009.01.011

Cited by 27 publications

(30 citation statements)

References 38 publications

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“…Various techniques have been developed to provide homogeneous dose distribution in PTV, for example, FIF, FP-IMRT, and IP-IMRT. [67891011121314] The FIF technique is a practical method and less operator-dependent. However, the procedures used to optimize the plans for WBRT have not been well established at our institution.…”

Section: Discussionmentioning

confidence: 99%

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Improvement of dose distribution with irregular surface compensator in whole breast radiotherapy

et al. 2013

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Aim of this study was to compare the dosimetric aspects of whole breast radiotherapy (WBRT) between an irregular surface compensator (ISC) and a conventional tangential field technique using physical wedges. Treatment plans were produced for 20 patients. The Eclipse treatment planning system (Varian Medical Systems) was used for the dose calculation: For the physical wedge technique, the wedge angle was selected to provide the best dose homogeneity; for the ISC technique, the fluence editor application was used to extend the optimal fluence. These two treatment plans were compared in terms of doses in the planning target volume, the dose homogeneity index, the maximum dose, ipsilateral lung and heart doses for left breast irradiation, and the monitor unit counts required for treatment. Compared with the physical wedge technique, the ISC technique significantly reduced the dose homogeneity index, the maximum dose, the volumes received at 105% of the prescription dose, as well as reducing both the ipsilateral lung and heart doses (P < 0.01 for all comparisons). However, the monitor unit counts were not significantly different between the techniques (P > 0.05). Thus, the ISC technique for WBRT enables significantly better dose distribution in the planning target volume.

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Section: Discussionmentioning

confidence: 99%

“…These include the field-in-field (FIF) technique, the use of electronic compensation and inverse planning intensity modulated radiation therapy (IP-IMRT). [67891011121314]…”

Section: Introductionmentioning

confidence: 99%

Improvement of dose distribution with irregular surface compensator in whole breast radiotherapy

et al. 2013

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“…Several studies have demonstrated that hybrid IMRT achieved comparable dosimetric outcomes as FP FIF IMRT with comparable treatment planning time 18–21…”

Section: Types Of Breast Imrt Techniquesmentioning

confidence: 99%

“…Descovich et al18 compared a hybrid direct aperture optimized (hDAO) IP IMRT to FP FIF IMRT for WBE-BRT 18. Both hDAO IP IMRT and FP FIF IMRT utilized two tangential beam directions.…”

Section: Types Of Breast Imrt Techniquesmentioning

confidence: 99%

Intensity-modulated radiation therapy for early-stage breast cancer: is it ready for prime time?

Chan¹,

Tan²,

Tang³

2017

BCTT

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Whole breast external beam radiotherapy (WBEBRT) is commonly used as an essential arm in the treatment management of women with early-stage breast cancer. Dosimetry planning for conventional WBEBRT typically involves a pair of tangential fields. Advancement in radiation technology and techniques has the potential to improve treatment outcomes with clinically meaningful long-term benefits. However, this advancement must be balanced with safety and improved efficacy. Intensity-modulated radiation therapy (IMRT) is an advanced technique that shows promise in improving the planning process and radiation delivery. Early data on utilizing IMRT for WBEBRT demonstrate more homogenous dose distribution with reduction in organs at risk doses. This translates to toxicities reduction. The two common descriptors for IMRT are forward-planning “fields in field” and inverse planning. Unlike IMRT for other organs, the aim of IMRT for breast planning is to achieve dose homogeneity and not organ conformality. The aim of this paper was to evaluate whether IMRT is ready for prime time based on these three points: 1) workload impact, 2) the clinical impact on the patient’s quality of life, and 3) the appropriateness and applicability to clinical practice.

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“…With the increasing clinical use of radiotherapy techniques that rely on the accurate spatial and temporal variation of dose delivery [1][2][3][4][5] there is a growing need for the ability to fully characterise a radiation field, in four dimensions.…”

Section: Introductionmentioning

confidence: 99%

A hybrid radiation detector for simultaneous spatial and temporal dosimetry

Poole

Trapp

Kenny

et al. 2011

Australas Phys Eng Sci Med

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In this feasibility study an organic plastic scintillator is calibrated against ionisation chamber measurements and then embedded in a polymer gel dosimeter to obtain a quasi-4D radiation detector. This hybrid dosimeter was irradiated with megavoltage x-rays from a linear accelerator, with temporal measurements of the dose rate being acquired by the scintillator and spatial measurements acquired with the gel dosimeter. The detectors employed in this study are radiologically equivalent; and we show that neither detector perturbs the intensity of the radiation field of the other. By employing these detectors in concert, spatial and temporal variations in the radiation intensity can now be detected and gel dosimeters can be calibrated for absolute dose from a single irradiation.

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Comparison Between Hybrid Direct Aperture Optimized Intensity-Modulated Radiotherapy and Forward Planning Intensity-Modulated Radiotherapy for Whole Breast Irradiation

Cited by 27 publications

References 38 publications

Improvement of dose distribution with irregular surface compensator in whole breast radiotherapy

Improvement of dose distribution with irregular surface compensator in whole breast radiotherapy

Intensity-modulated radiation therapy for early-stage breast cancer: is it ready for prime time?

A hybrid radiation detector for simultaneous spatial and temporal dosimetry

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