2008
DOI: 10.1590/s0036-46652008000100002
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Comparison between E-test and CLSI broth microdilution method for antifungal susceptibility testing of Candida albicans oral isolates

Abstract: SUMMARYThirty Candida albicans isolated from oral candidosis patients and 30 C. albicans isolated from control individuals were studied. In vitro susceptibility tests were performed for amphotericin B, fluconazole, 5-flucytosine and itraconazole through the Clinical and Laboratorial Standards Institute (CLSI) reference method and E test system. The results obtained were analyzed and compared. MIC values were similar for the strains isolated from oral candidosis patients and control individuals. The agreement r… Show more

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Cited by 21 publications
(13 citation statements)
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“…It can easily be used, on a large scale, by laboratories with few technological features. Other techniques such as disk diffusion, E-test, colorimetric methods are used; however, the broth dilution method is considered the standard practice due to its good reproducibility (Koga-Ito et al, 2008).…”
Section: Discussionmentioning
confidence: 99%
“…It can easily be used, on a large scale, by laboratories with few technological features. Other techniques such as disk diffusion, E-test, colorimetric methods are used; however, the broth dilution method is considered the standard practice due to its good reproducibility (Koga-Ito et al, 2008).…”
Section: Discussionmentioning
confidence: 99%
“…E-test has been considered as an alternative to the reference broth microdilution method (CLSI) for its practicability and reproducibility [14]- [16]. It is easy, fast, and can be used by the gynecologist for increased reliability of prescription medication, especially in more complicated cases [15]- [17].…”
Section: Introductionmentioning
confidence: 99%
“…Oral candidiasis is recently increasing due to old age, denture use, diabetes, systemic steroid and antibiotic use, pernicious anemia, malignancy, radiation therapy on the head and neck, and cell-mediated immunodeficiency 1 2 . With the increasing use of antifungal agents, several reports on antifungal resistance have been published 3 4 5 6 7 8 9 10 11 12 13 14 15 . Therefore, antifungal susceptibility testing becomes necessary for the effective treatment of oral candidiasis.…”
Section: Introductionmentioning
confidence: 99%