Comparison between dynamic susceptibility contrast magnetic resonance imaging and arterial spin labeling techniques in distinguishing malignant from benign brain tumors

Ata, Emine Sevcan; Turğut, Mehmet; Eraslan, Cenk; Dayanir, Yelda Özsunar

doi:10.1016/j.ejrad.2016.05.015

Cited by 23 publications

(22 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although ASL is not as widely utilized as DCE-MRI, there continue to be advances in this technique with a promising outlook for future application in glioma imaging. 21 …”

Section: Advanced Mri Techniquesmentioning

confidence: 99%

Conventional and advanced magnetic resonance imaging in patients with high-grade glioma

Pope¹,

Brandal²

2018

Q J Nucl Med Mol Imaging

View full text Add to dashboard Cite

Magnetic resonance imaging is integral to the care of patients with high-grade gliomas. Anatomic detail can be acquired with conventional structural imaging, but newer approaches also add capabilities to interrogate image-derived physiologic and molecular characteristics of central nervous system neoplasms. These advanced imaging techniques are increasingly employed to generate biomarkers that better reflect tumor burden and therapy response. The following is an overview of current strategies based on advanced magnetic resonance imaging that are used in the assessment of high-grade glioma patients with an emphasis on how novel imaging biomarkers can potentially advance patient care.

show abstract

“…Although ASL is not as widely utilized as DCE-MRI, there continue to be advances in this technique with a promising outlook for future application in glioma imaging. 21 …”

Section: Advanced Mri Techniquesmentioning

confidence: 99%

Conventional and advanced magnetic resonance imaging in patients with high-grade glioma

Pope¹,

Brandal²

2018

Q J Nucl Med Mol Imaging

View full text Add to dashboard Cite

show abstract

“…4 Previous studies have shown a very strong correlation between ASL and DSC-MRI derived perfusion parameters for evaluation of brain tumors and support the possibility that ASL can be used as an alternative to DSC-MRI. [5][6][7] Gliomas are the most common primary brain tumors and sometimes differentiation from solitary enhancing cerebral metastases can be difficult on conventional MRI. Primary tumors have shown statistically significant higher perfusion in perilesional edema (PE) compared to metastases that have been ascribed to tumor infiltration along white matter tracts in glioma.…”

Section: Introductionmentioning

confidence: 99%

Arterial spin labeling perfusion: Prospective MR imaging in differentiating neoplastic from non-neoplastic intra-axial brain lesions

et al. 2018

View full text Add to dashboard Cite

show abstract

“…In clinical practice, pCASL provide some quantitative and qualitative measurements of blood hemodynamics in brain tissue such as blood volume, blood velocities, and blood transit times (69). There is substantial evidence supporting that measurements obtained from DCS and pCASL techniques are comparable and their diagnostic performance is similar (70, 71). The most notable metric in pCASL is CBF, being the tumor blood volume directly proportional with the tumor grade (72, 73).…”

Section: Current Status Of Glioblastoma Response Assessmentmentioning

confidence: 89%

Assessment of Glioblastoma Response in the Era of Bevacizumab: Longstanding and Emergent Challenges in the Imaging Evaluation of Pseudoresponse

et al. 2019

View full text Add to dashboard Cite

Glioblastoma is the deadliest primary malignant brain neoplasm, and despite the availability of many treatment options, its prognosis remains somber. Enhancement detected by magnetic resonance imaging (MRI) was considered the best imaging marker of tumor activity in glioblastoma for decades. However, its role as a surrogate marker of tumor viability has changed with the appearance of new treatment regimens and imaging modalities. The antiangiogenic therapy created an inflection point in the imaging assessment of glioblastoma response in clinical trials and clinical practice. Although BEV led to the improvement of enhancement, it did not necessarily mean tumor response. The decrease in the enhancement intensity represents a change in the permeability properties of the blood brain barrier, and presumably, the switch of the tumor growth pattern to an infiltrative non-enhancing phenotype. New imaging techniques for the assessment of cellularity, blood flow hemodynamics, and biochemistry have emerged to overcome this hurdle; nevertheless, designing tools to assess tumor response more accurately, and in so doing, improve the assessment of response to standard of care (SOC) therapies and to novel therapies, remains challenging.

show abstract

Comparison between dynamic susceptibility contrast magnetic resonance imaging and arterial spin labeling techniques in distinguishing malignant from benign brain tumors

Cited by 23 publications

References 31 publications

Conventional and advanced magnetic resonance imaging in patients with high-grade glioma

Conventional and advanced magnetic resonance imaging in patients with high-grade glioma

Arterial spin labeling perfusion: Prospective MR imaging in differentiating neoplastic from non-neoplastic intra-axial brain lesions

Assessment of Glioblastoma Response in the Era of Bevacizumab: Longstanding and Emergent Challenges in the Imaging Evaluation of Pseudoresponse

Contact Info

Product

Resources

About