Comparison between connective tissue graft and xenogeneic acellular dermal matrix to treat single gingival recession: A data reanalysis of randomized clinical trials

Abstract

Objectives There are few studies comparing xenogeneic acellular dermal matrixes (XDMs) with connective tissue graft (CTG) to treat single gingival recession (GR). The present study involved a reanalysis of previous studies and comparison of CTG or XDM to treat single RT1/GR. Materials and methods Fifty patients from three previous randomized clinical trials treated either by CTG (n = 25) or XDM (n = 25) were evaluated after 6‐month. Clinical, patient‐centered, and esthetic parameters were assessed. Pearson's correlation and regression analyses were also performed. Results Greater recession reduction (RecRed), percentage of root coverage (%RC), and complete root coverage (CRC) were observed in the CTG group (p ≤ 0.02). Gingival thickness (GT) and keratinized tissue width (KTW) gains were higher in the CTG group. The CTG group showed better esthetic at 6‐month. Logistic analyses reported that GT([OR] = 1.6473) and papilla height (PH) (OR = 8.20) are predictors of CRC. GT*XDM interaction was a negative predictor of CRC (OR = 7.105−5). GT at baseline acted as a predictor of RecRed in both groups (p = 0.03). The XDM graft impacted RecRed and %RC negatively. Baseline PH was a predictor of %RC for both grafts. Conclusion CTG was superior for treating RT1/GR, providing better root coverage outcomes and tissue gains over time. GT, PH, and graft type were classified as predictors of CRC. Clinical significance CTG presented better outcomes to treat single RT1 gingival recession when compared to the XDM.

Periodontal Phenotype Modification Using Subepithelial Connective Tissue Graft and Bone Graft in the Mandibular Anterior Teeth with Mucogingival Problems Following Orthodontic Treatment

“…In several root coverage procedures, a coronally advanced flap with a subepithelial connective tissue graft is considered the gold standard [ 11 , 13 ]. In addition, alternatives such as acellular dermal matrix and collagen matrix are used with a coronally advanced flap to reduce morbidity at the donor site [ 27 , 28 , 29 ]. Although some clinical advantages have been reported, this procedure is not as effective as a coronally advanced flap with a subepithelial connective tissue graft [ 28 , 30 ].…”

Multiple gingival recessions associated with non‐carious cervical lesions treated by partial restoration and modified coronally advanced flap with either connective tissue graft or xenogeneic acellular dermal matrix: A randomized clinical trial

“…Even though direct comparisons cannot be made, when the results of the present study are compared to other studies that evaluated the XDMs to treat GR with intact tooth surface (without NCCL), similar results are observed. Miguel et al 40 showed that CAF+CTG was superior to CAF+XDM for treating single GRs. Pietruska et al 41 also observed superior results for CTG compared to XDM when multiple recessions were treated and the modified coronally advanced tunnel technique was applied in both groups.…”

“…Even though direct comparisons cannot be made, when the results of the present study are compared to other studies that evaluated the XDMs to treat GR with intact tooth surface (without NCCL), similar results are observed. Miguel et al 40 . showed that CAF+CTG was superior to CAF+XDM for treating single GRs.…”