Comparison Between 30:1 and 30:2 Compression‐to‐ventilation Ratios for Cardiopulmonary Resuscitation: Are Two Ventilations Necessary?

Abstract

Objectives: Controversy is continuing over the need for ventilation and the optimal compressionventilation (CV) ratio during cardiopulmonary resuscitation (CPR). The aim of this study was to comparatively elucidate the effect on hemodynamics and arterial oxygen saturation of a single ventilation relative to two consecutive ventilations during CPR in a dog model of cardiac arrest.Methods: Twenty mongrel dogs were divided into two groups. After 3 minutes of ventricular fibrillation (VF), the single-ventilation group received CPR with a 30:1 CV ratio, and the two-ventilation group received CPR with a 30:2 CV ratio, all with room air for 7 minutes. Thereafter, continuous chest compressions and intermittent ventilation at rate of 10 per minute were followed for both groups for 10 minutes. Hemodynamic parameters, arterial blood gas profiles, and variables from CPR were compared at baseline and at 5, 10, 15, and 20 minutes after induction of VF.

Single Ventilation during Cardiopulmonary Resuscitation Results in Better Neurological Outcomes in a Porcine Model of Cardiac Arrest

“…Meanwhile, in other studies, an increased CV ratio from 15:2 or 30:2 to 15:1 showed better hemodynamics and lower oxygen uptake and energy expenditure during CPR. 13 17 27 In our study, the CV1 group showed a higher CCF than that in the CV2 group and higher oxygenation than that of the CC group during BLS. Minimal interruption of chest compression for ventilation resulted in higher CCF and a lesser CP drop in the CV1 group, compared to the CV2 group.…”

“…Recently our group reported that a single ventilation (30:1 CV ratio, CV1) can have similar oxygenation and better chest compression fraction (CCF) than those of a two ventilations (30:2 CV ratio) and could be an alternative CPR method to minimize interruption of chest compression and maintain oxygenation. 17 However, this study did not verify the effect of 30:1 CV ratio on neurologic outcomes, which are more meaningful to clinical practice. The aim of this study was to compare short-term resuscitation outcomes among CPR using the 30:1 and 30:2 CV ratio and chest compression-only CPR, and we hypothesized that 30:1 CV ratio would show better neurologic outcomes.…”

Effect of physical fatigue and smoking cigarettes on the CPR effectiveness performed by soldiers

“…Research results indicate that the optimization of procedures plays a key role in saving the lives of patients who have had a cardiac arrest [11]. The importance and impact of the quality of CPR and its parameters on the survival of patients are also emphasized [16][17][18][19].…”