Comparison and Assessment of Flixweed and Fig Effects on Irritable Bowel Syndrome with Predominant Constipation: A Single-Blind Randomized Clinical Trial

Pourmasoumi, Makan; Ghiasvand, Reza; Darvishi, Leila; Hadi, Amir; Esfahani, Nimah Bahreini; Keshavarzpour, Ziyaaddin

doi:10.1016/j.explore.2018.09.003

Cited by 15 publications

(15 citation statements)

References 38 publications

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“…In this regard, finding an effective approach or adjuvant remedy, which could reduce the cost of treatment, as well as decrease the adverse effects of pharmacological agents, remains of paramount importance (Karimian, Hadi, Pourmasoumi, Najafgholizadeh, & Ghavami, 2019). In contemporary research and practice, medicinal plants have garnered interest, largely due to their purported beneficial effects on diseases, along with their overall lower cost and side effects in comparison to synthetic drugs (Clark, Ghaedi, Arab, Pourmasoumi, & Hadi, 2019; Pourmasoumi et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

The effect of okra (Abelmoschus esculentus) on lipid profiles and glycemic indices in Type 2 diabetic adults: Randomized double blinded trials

Moradi

Tarrahi

Ghasempour

et al. 2020

Phytotherapy Research

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The aim of the present study was to investigate the effect of okra consumption on serum levels of lipid profiles and glycemic indices in Type 2 diabetic (T2D) patients. The present study was a randomized, double-blinded clinical trial, carried out in Kerman, Iran. Sixty T2D patients were randomized into intervention and control groups and received 10 g okra powder blended in 150 g conventional yogurt or conventional yogurt alone, along with dinner and lunch, for 8 weeks. Glycemic markers and lipid profile were assessed, as well as anthropometric measures, at the beginning and end of study. The findings showed that 8 weeks okra consumption resulted in a significant decrease in fasting plasma glucose (−15.61 ± 19.44 vs. −3.40 ± 24.78; p = .02), homeostatic model of assessment for insulin resistance (−1.17 ± 1.61 vs. −0.14 ± 1.64; p = .01), quantitative insulin sensitivity check index (0.01 ± 0.007 vs. 0.00 ± 0.01; p = .004), triacylglycerol (−22.30 ± 32.46 vs. −3.86 ± 30.57; p = .001), total cholesterol (−10.23 ± 10.36 vs. −2.03 ± 13.94; p = .004), low-density lipoprotein cholesterol (LDL-C; −8.15 ± 10.01 vs. −2.31 ± 9.37; p = .02), and LDL-C/high-density lipoprotein cholesterol (HDL-C) ratio (−0.28 ± 0.37 vs. −0.08 ± 0.24; p = .01). No significant difference was observed between groups in HDL-C, glycated hemoglobin, fasting insulin levels, and anthropometric measures. The present study suggests that okra consumption can elicit improvements in lipid profile, as well as glycemic markers, among T2D patients.

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Section: Introductionmentioning

confidence: 99%

The effect of okra (Abelmoschus esculentus) on lipid profiles and glycemic indices in Type 2 diabetic adults: Randomized double blinded trials

Moradi

Tarrahi

Ghasempour

et al. 2020

Phytotherapy Research

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“…A recent RCT from Iran compared rehydrated figs (90 g/d) or flixweed (60 g/d) with placebo for 4 months in 150 patients with IBS-C. Both interventions led to significant improvements in stool frequency, stool consistency, and the frequency but not severity of abdominal pain ( 82 ).…”

Section: The Lfdmentioning

confidence: 99%

The Role of Food in the Treatment of Bowel Disorders: Focus on Irritable Bowel Syndrome and Functional Constipation

2022

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Irritable bowel syndrome (IBS) and functional constipation (FC) are among the most common disorders of gut–brain interaction, affecting millions of individuals worldwide. Most patients with disorders of gut–brain interaction perceive food as a trigger for their gastrointestinal symptoms, and specific dietary manipulations/advice have now been recognized as a cornerstone therapeutic option for IBS and FC. We discuss in detail the 2 most common dietary interventions used for the management of IBS-general dietary advice based on the National Institute for Health and Care Excellence guidelines and a diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs). We summarize the literature around the possible mechanisms of FODMAP-mediated IBS pathophysiology, the current 3-step, top-down approach of administering a low FODMAP diet (LFD) (restriction phase, followed by reintroduction and personalization), the efficacy data of its restriction and personalization phases, and possible biomarkers for response to an LFD. We also summarize the limitations and challenges of an LFD along with the alternative approach to administering an LFD (e.g., bottom-up). Finally, we discuss the available efficacy data for fiber, other dietary interventions (e.g., Mediterranean diet, gluten-free diet, and holistic dietary interventions), and functional foods (e.g., kiwifruit, rhubarb, aloe, and prunes) in the management of IBS and FC.

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“…In long-term care residents, a natural laxative mixture with 1 cup figs was more effective than daily prescribed laxatives at increasing defecation frequency (p=0.007) 35 . In Iran, adults consuming fig or flixweed had significant improvements in IBS-C symptoms including frequency of defecation and hard stools compared with a control group (p<0.05) 36 .…”

Section: Figurementioning

confidence: 93%

Comparison of the role of fiber in the treatment of functional constipation in children and adults

Axelrod¹

2019

NGL

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El estreñimiento funcional es uno de los trastornos gastrointestinales más frecuentes en los niños y adultos. El aumento del consumo de agua y fibra son algunas de las recomendaciones mas comúnmente dadas a los pacientes. Una mayor ingesta de fibra se puede lograr a través del consumo de alimentos ricos en fibra dietética, o tomado en forma suplementaria. Además de las fibras que ocurren naturalmente en los alimentos, la Administración de Drogas y Alimentos (FDA) de los Estados Unidos ha aprobado más de 14 fibras aisladas o sintéticas para su uso. Hoy en día existen pocas investigaciones que hayan estudiado el beneficio de todos estos tipos de fibra para el tratamiento del estreñimiento en niños y adultos. Esta revisión discute la evidencia de los diferentes tipos de fibra para el tratamiento del estreñimiento funcional en niños y adultos. (NeuroGastroLatam Rev. 2018;2:149-168).

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Comparison and Assessment of Flixweed and Fig Effects on Irritable Bowel Syndrome with Predominant Constipation: A Single-Blind Randomized Clinical Trial

Cited by 15 publications

References 38 publications

The effect of okra (Abelmoschus esculentus) on lipid profiles and glycemic indices in Type 2 diabetic adults: Randomized double blinded trials

The effect of okra (Abelmoschus esculentus) on lipid profiles and glycemic indices in Type 2 diabetic adults: Randomized double blinded trials

The Role of Food in the Treatment of Bowel Disorders: Focus on Irritable Bowel Syndrome and Functional Constipation

Comparison of the role of fiber in the treatment of functional constipation in children and adults

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